208726

Calpain Inhibitor V

The Calpain Inhibitor V controls the biological activity of Calpain. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

• Synonym(s): Calpain Inhibitor V, Mu-Val-HPh-FMK
• Empirical Formula (Hill Notation): C₂₁H₃₀FN₃O₄
• Molecular Weight: 407.48
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• Quality Level: 100
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated
• color: orange-yellow
• solubility: DMSO: 25 mg/mL
• shipped in: ambient
• storage temp.: −20°C

Description

General description

A potent, cell-permeable, and irreversible inhibitor of calpain.

Biochem/physiol Actions

Cell permeable: yes

Primary Target
calpain

Product does not compete with ATP.

Reversible: no

Warning

Toxicity: Standard Handling (A)

Sequence

Mu-Val-HPh-CH₂F (Mu = morpholinoureidyl; HPh = homophenylalanyl)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Analysis Note

single spot by TLC

Other Notes

Esser, R.E., et al. 1994. Arthritis Rheum. 37, 236.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable