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810241C

Avanti

TopFluor™ TMR PE

Avanti Research™ - A Croda Brand 810241C

Synonym(s):

1-oleoyl-2-(6-((4,4-difluoro-1,3-dimethyl-5-(4-methoxyphenyl)-4-bora-3α,4α-diaza-s-indacene-2-propionyl)amino)hexanoyl)-sn-glycero-3- phosphoethanolamine

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About This Item

Empirical Formula (Hill Notation):
C50H76 BF2N4 O10P
Molecular Weight:
972.94
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (810241C-1mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 810241C

concentration

1 mg/mL (810241C-1mg)

shipped in

dry ice

storage temp.

−20°C

General description

TopFluor™ TMR PE is an acyl-chain-modified fluorescent phospholipid. L-α-Phosphatidylethanolamine (PE) is a membrane phospholipid and is the second most abundant phospholipid in animals, plants and yeast. It is the major lipid in bacteria.

Application

TopFluor™ TMR PE is suitable to use as a component of vesicle and a donor-acceptor for fluorescence quenching. It is also suitable for the formation of lipid membrane.

Biochem/physiol Actions

L-α-Phosphatidylethanolamine (PE) is essential for maintaining the structural integrity of membranes. TopFluor™ TMR PE is useful for cellular labelling.

Packaging

5 mL Amber Glass Screw Cap Vial (810241C-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system

WGK

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Single-molecule analysis of phospholipid scrambling by TMEM16F
Watanabe R, et al.
Proceedings of the National Academy of Sciences of the USA (2018)
Ann C Kimble-Hill et al.
The journal of physical chemistry. B, 122(35), 8404-8415 (2018-06-08)
Phosphatidylinositol (PI) lipids are necessary for many cellular signaling pathways of membrane associated proteins, such as angiomotin (Amot). The Amot family regulates cellular polarity, growth, and migration. Given the low concentration of PI lipids in these membranes, it is likely
Phosphatidylserine and phosphatidylethanolamine in mammalian cells: two metabolically related aminophospholipids
Vance JE
Journal of Lipid Research, 49(7), 1377-1387 (2008)
Formation and function of phosphatidylserine and phosphatidylethanolamine in mammalian cells
Vance JE and Tasseva G
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1831(3), 543-554 (2013)

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