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S5553

Sigma-Aldrich

Succinimide

98%

Synonym(s):

2,5-Pyrrolidinedione

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About This Item

Empirical Formula (Hill Notation):
C4H5NO2
CAS Number:
Molecular Weight:
99.09
Beilstein:
108440
EC Number:
MDL number:
UNSPSC Code:
12352103

Assay

98%

bp

285-290 °C (lit.)

mp

123-125 °C (lit.)

SMILES string

O=C1CCC(=O)N1

InChI

1S/C4H5NO2/c6-3-1-2-4(7)5-3/h1-2H2,(H,5,6,7)

InChI key

KZNICNPSHKQLFF-UHFFFAOYSA-N

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Description
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Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Zhiwei Lin et al.
Physical chemistry chemical physics : PCCP, 14(30), 10445-10454 (2012-05-05)
Dual-frequency relaxation-assisted two-dimensional infrared (RA 2DIR) spectroscopy was used to investigate energy transport in polyethylene glycol (PEG) oligomers of different length, having 0, 4, 8, and 12 repeating units and end-labeled with azido and succinimide ester moieties (azPEGn). The energy
Yutaka Sadakane et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(29), 3240-3246 (2011-04-08)
The major soluble eye lens protein, αA-crystallin, has a very long half-life. Thus, many post-translational modifications, including stereoinversion, have been found in its constituent amino acids. We determine the rates of β-linkage isomerization, which is the main reaction through the
Yann Desfougères et al.
Biomacromolecules, 12(1), 156-166 (2010-12-21)
Protein chemical degradations occur naturally into living cells as soon as proteins have been synthesized. Among these modifications, deamidation of asparagine or glutamine residues has been extensively studied, whereas the intermediate state, a succinimide derivative, was poorly investigated because of
Ohgi Takahashi et al.
Chemistry & biodiversity, 7(6), 1630-1633 (2010-06-22)
The rapid racemization of aspartic acid (Asp) residues in peptides and proteins is due mainly to the succinimide intermediate. However, there should be another mechanism for Asp racemization without intermediacy of the succinimide. The direct H-atom abstraction from the C(alpha)-atom
Srinivasa Reddy Mothe et al.
The Journal of organic chemistry, 76(8), 2521-2531 (2011-03-15)
A one-pot, two-step method to prepare 3-halohydrofurans efficiently by TfOH-catalyzed hydroxylation/halocyclization of cyclopropyl methanols with H(2)O and N-halosuccinimide (NXS, X=1, Br, Cl) or Selectfluor is described. The reactions proceed rapidly under mild and operationally straightforward conditions with a catalyst loading

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