All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C8H6N2OS
CAS Number:
Molecular Weight:
178.21
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
Assay
97%
form
liquid
mp
>300 °C (lit.)
SMILES string
SC1=Nc2ccccc2C(=O)N1
InChI
1S/C8H6N2OS/c11-7-5-3-1-2-4-6(5)9-8(12)10-7/h1-4H,(H2,9,10,11,12)
InChI key
PUPFOFVEHDNUJU-UHFFFAOYSA-N
General description
The FTIR and FT-Raman spectra of 2-mercapto-4(3H) quinazolinone has been studied. Alkylation of 2-mercapto-4(3H)-quinazolinone has been reported.
Application
2-Mercapto-4(3H)-quinazolinone was employed as a modifier for the carbon paste electrode, for voltammetric determination of mercury. It was used in the synthesis of 4-quinazolinone derivatives, inhibitors of the DNA repair enzyme poly(ADP-ribose) polymerase.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Stripping voltammetric determination of trace amounts of mercury using a carbon paste electrode modified with 2-mercapto-4 (3H)-quinazolinone.
Cai X, et al.
Microchimica Acta, 112(1-4), 135-146 (1993)
N Prabavathi et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 129, 572-583 (2014-05-13)
The FTIR and FT-Raman spectra of 2-mercapto-4(3H) quinazolinone have been recorded in the region 4000-450 and 4000-100 cm(-1), respectively. The optimized geometry, frequency and intensity of the vibrational bands of 2-mercapto-4(3H) quinazolinone (2MQ) were obtained by the density functional theory
Synthesis and study of new 4-quinazolinone inhibitors of the DNA repair enzyme poly (ADP-ribose) polymerase (PARP).
Kulcsar G, et al.
ARKIVOC (Gainesville, FL, United States), 121, 131-131 (2003)
Tomás Lombardo et al.
Basic & clinical pharmacology & toxicology, 122(5), 489-500 (2017-12-06)
Collapse of the mitochondrial membrane potential (MMP) is often considered the initiation of regulated cell death (RCD). Carbonyl cyanide 3-chlorophenylhydrazone (CCCP) is an uncoupler of the electron transport chain (ETC) that facilitates the translocation of protons into the mitochondrial matrix
Monize M da Silva et al.
Dalton transactions (Cambridge, England : 2003), 48(39), 14885-14897 (2019-09-27)
Herein we discuss five ruthenium(ii) complexes with good cytotoxicity against cancer cells. These complexes are named [Ru(tzdt)(bipy)(dppb)]PF6 (1), [Ru(mmi)(bipy)(dppb)]PF6 (2), [Ru(dmp)(bipy)(dppb)]PF6 (3), [Ru(mpca)(bipy)(dppb)]PF6 (4) and [Ru(2mq)(bipy)(dppb)]PF6 (5), where tzdt = 1,3-thiazolidine-2-thione, mmi = mercapto-1-methyl-imidazole, dmp = 4,6-diamino-2-mercaptopyrimidine, mpca = 6-mercaptopyridine-3-carboxylic
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service