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Z2902

Sigma-Aldrich

Zinc Formalin Fixative

fixative, pH 6.2-6.3

Synonym(s):

ZFF

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About This Item

UNSPSC Code:
12171500
NACRES:
NA.47

pH

6.2-6.3

application(s)

hematology
histology

storage temp.

room temp

General description

Zinc Formalin Fixative is a non-precipitating fixative. This fixative is compatible with histochemical, immunochemical and special stains. It may be used with automated tissue processors and also in manual methods. The zinc chloride component of the formulation increases the rigidity of cellular components to withstand subsequent processing, sectioning and staining procedures. Tissue specimens initially fixed using 10% neutral buffered formalin solution may be post-fixed using the Zinc Formalin Fixative.

Application

Zinc Formalin Fixative is an excellent morphological preservation of nuclear and cytoplasmic components. Can replace neutral buffered formalin for routine tissue and immunohistochemical procedures. It is a non-precipitating fixative which can be used with automated and manual methods.

Preparation Note

The Zinc Formalin Fixative is supplied ready-to-use.

Storage and Stability

Store the product at room temperature. Do not freeze.

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 1B - Eye Dam. 1 - Muta. 2 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Tandem bispecific neutralizing antibody eliminates HIV-1 infection in humanized mice.
Wu X, et al.
The Journal of Clinical Investigation (2018)
Vignesh Murugesan et al.
Journal of vascular research, 54(4), 235-245 (2017-08-03)
Smooth muscle cells are important for atherosclerotic plaque stability. Their proper ability to communicate with the extracellular matrix is crucial for maintaining the correct tissue integrity. In this study, we have investigated the role of β-sarcoglycan within the matrix-binding dystrophin-glycoprotein
Causes, diagnostics, and distribution of an ongoing penaeid shrimp black gill epidemic in the US South Atlantic Bight.
Frischer M E, et al.
Journal of shellfish research., 36(2), 487-500 (2017)
Megan N Fitch et al.
Environmental research, 181, 108913-108913 (2019-11-23)
Air pollution exposure is known to contribute to the progression of cardiovascular disease (CVD) and there is increasing evidence that dysbiosis of the gut microbiome may also play a role in the pathogenesis of CVD, including atherosclerosis. To date, the
Miguel Sampedro-Núñez et al.
Cancers, 12(10) (2020-10-18)
Cancer cells develop mechanisms that increase nutrient uptake, including key nutrient carriers, such as amino acid transporter 1 (LAT-1) and glucose transporter 1 (GLUT-1), regulated by the oxygen-sensing Von Hippel Lindau-hypoxia-inducible factor (VHL-HIF) transcriptional pathway. We aimed to analyze these

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