SAB4300317

Anti-ATF2 (Ab-112 or 94) antibody produced in rabbit

affinity isolated antibody

• Synonym(s): Anti-CRE-BP1 antibody produced in rabbit, Anti-CREB2 antibody produced in rabbit, Anti-HB16 antibody produced in rabbit, Anti-MGC111558 antibody produced in rabbit, Anti-activating transcription factor 2 antibody produced in rabbit
• UNSPSC Code: 12352203
• NACRES: NA.43

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: 65-75 kDa
• species reactivity: mouse, rat, human
• concentration: 1 mg/mL
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; western blot: 1:500-1:1000
• isotype: IgG
• immunogen sequence: (D-L-S-P-L)
• NCBI accession no.: NP_001871.2
• UniProt accession no.: P15336
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... ATF2(1386)

Description

Immunogen

Peptide sequence around aa. 110-114 or 92-96 (D-L-S-P-L), according to the protein ATF2.

Features and Benefits

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Target description

Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2-c-Jun complex.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable