P5660

3-sn-Phosphatidyl-L-serine sodium salt from bovine brain

≥95% (TLC)

• Synonym(s): 1,2-Diacyl-sn-glycero-3-phospho-L-serine, L-α-Phosphatidyl-L-serine sodium salt
• MDL number: MFCD00077390
• UNSPSC Code: 12352200
• PubChem Substance ID: 24898688
• NACRES: NA.77

Properties

• Assay: ≥95% (TLC)
• form: powder
• storage temp.: −20°C
• SMILES string: [Na+].CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)OC[C@H](N)C([O-])=O)OC(=O)CCCCCCCCCCCCCCCCC
• InChI: 1S/C42H82NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(44)50-35-38(36-51-54(48,49)52-37-39(43)42(46)47)53-41(45)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h38-39H,3-37,43H2,1-2H3,(H,46,47)(H,48,49);/q;+1/p-1/t38-,39+;/m1./s1
• InChI key: SJRBMGBLPUBGJL-MBAWARMDSA-M

Description

General description

Phosphatidylserine is an anionic phospholipid, which is found on the plasma membrane. Exposure of phosphatidylserine on the surface of plasma membrane stimulates the removal of apoptotic and red blood cells. It regulates the production of thrombin and maintains hemostasis.

Application

3-sn-Phosphatidyl-L-serine sodium salt from bovine brain has been used as a glycosylphosphatidylinositol (GPI)-anchor control.

Biochem/physiol Actions

A slowly metabolized structural phospholipid found mainly in gray matter.

Caution

Solutions exposed to room temperature will decompose about 0.5% per day.

Preparation Note

Washed with EDTA and converted to a sodium salt.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves