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Key Documents

L5670

Sigma-Aldrich

Locostatin

≥98% (HPLC)

Synonym(s):

(4S)-3-[(E)-1-Oxo-2-butenyl]-4-(phenylmethyl)-2-oxazolidinone, (4S)-3-[(E)-But-2-enoyl]-4-benzyl-2-oxazolidinone, UIC-1005

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About This Item

Empirical Formula (Hill Notation):
C14H15NO3
CAS Number:
Molecular Weight:
245.27
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Pricing and availability is not currently available.

Quality Level

Assay

≥98% (HPLC)

form

powder

color

white to off-white

solubility

DMSO: ≥30 mg/mL

storage temp.

2-8°C

SMILES string

C\C=C\C(=O)N1[C@H](COC1=O)Cc2ccccc2

InChI

1S/C14H15NO3/c1-2-6-13(16)15-12(10-18-14(15)17)9-11-7-4-3-5-8-11/h2-8,12H,9-10H2,1H3/b6-2+/t12-/m0/s1

InChI key

UTZAFVPPWUIPBH-QSLRECBCSA-N

Biochem/physiol Actions

Locostatin is a cell permeable, potent inhibitor of Raf kinase inhibitor protein (RKIP)/Raf1 kinase interaction and an inhibitor of cell migration.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3


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