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About This Item
Empirical Formula (Hill Notation):
C12H24N2O3
CAS Number:
Molecular Weight:
244.33
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
form
solid
technique(s)
HPLC: suitable
mass spectrometry (MS): suitable
storage temp.
−20°C
SMILES string
CC(C)C[C@H](N)C(=O)N[C@H](CC(C)C)C(O)=O
InChI
1S/C12H24N2O3/c1-7(2)5-9(13)11(15)14-10(12(16)17)6-8(3)4/h7-10H,5-6,13H2,1-4H3,(H,14,15)(H,16,17)/t9-,10+/m0/s1
InChI key
LCPYQJIKPJDLLB-VHSXEESVSA-N
Application
Leu-D-Leu may be used as a reference peptide in the development of separation and detection technologies such as CE-ESI-MS.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Hongzhi Ye et al.
Electrophoresis, 31(20), 3400-3406 (2010-09-30)
In this article, an approach has been developed for the analysis of some small peptides with similar pI values by CE-ESI-MS based on the online concentration strategy of dynamic pH junction. The factors affected on the separation, detection and online
Joachim Vater et al.
Rapid communications in mass spectrometry : RCM, 23(10), 1493-1498 (2009-04-08)
An innovative technique to investigate the intermediates involved in the biosynthesis of the lipoheptapeptide surfactin from Bacillus subtilis OKB105 combining whole-cell matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS) with targeted generation of knock-out mutants was demonstrated. This method allows efficient
Hiroyuki Oku et al.
Biopolymers, 75(3), 242-254 (2004-08-19)
The depsipeptide Boc(1)-Leu(2)-Leu(3)-Ala(4)-Leu(5)-Leu(6)-Lac(7)-Leu(8)-Leu(9)-Lac(10)-Leu(11)-Leu(12)-Lac(13)-Leu(14)-Leu(15)-OEt(16) (1) (Boc = tert-butyloxycarbonyl, Lac = L-lactic acid residue) has been synthesized from the peptide Boc-Leu-Leu-Ala-OEt (2) and a depsipeptide, Boc-(Leu-Leu-Lac)(3)-Leu-Leu-OEt (3). Single crystals of 1 were successfully obtained and the structure has been solved by direct
S N Mitra et al.
Biopolymers, 34(9), 1139-1143 (1994-09-01)
The crystal structure of a dipeptide L-leucyl-L-leucine (C12H24N2O3) has been determined. The crystals are monoclinic, space group P2(1), with a = 5.434(4) A, b = 15.712(7) A, c = 11.275(2) A, beta = 100.41(1) degrees, and Z = 2. The
Y K Cho et al.
The Journal of biological chemistry, 273(38), 24305-24308 (1998-09-12)
Porcine pepsin proteolysis of the hexapeptide Leu-Ser-p-nitro-Phe-Nle-Ala-Leu-OMe (where OMe = methoxy and Nle = norleucine) in the presence of dipeptide Leu-Leu synthesizes a new hexapeptide Leu-Ser-p-nitro-Phe-Leu-Leu. Contrary to transpeptidation kinetics of other proteases, which depend upon an acyl-enzyme intermediate, the
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