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I9531

Sigma-Aldrich

Imiloxan hydrochloride

>98% (HPLC), solid

Synonym(s):

2-[(2,3-dihydro-1,4-benzodioxin-2yl)methyl]-1-ethyl-1H-imidazole hydrochloride, RS 21361

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About This Item

Empirical Formula (Hill Notation):
C14H16N2O2 · HCl
CAS Number:
Molecular Weight:
280.75
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

Assay

>98% (HPLC)

form

solid

color

white

solubility

H2O: soluble 30 mg/mL

SMILES string

Cl[H].CCn1ccnc1CC2COc3ccccc3O2

InChI

1S/C14H16N2O2.ClH/c1-2-16-8-7-15-14(16)9-11-10-17-12-5-3-4-6-13(12)18-11;/h3-8,11H,2,9-10H2,1H3;1H

InChI key

ANDJPJNFVJXEKX-UHFFFAOYSA-N

Gene Information

human ... ADRA2B(151)

Biochem/physiol Actions

Selective α2B-adrenoceptor antagonist.

Features and Benefits

This compound is featured on the α2-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Fatih İlkaya et al.
Pharmacology, biochemistry, and behavior, 122, 1-6 (2014-03-04)
It has been shown that imipramine, a tricyclic antidepressant (TCA), is a potent analgesic agent. However, the effect of imipramine on visceral pain has not been extensively investigated. In the current study, our aim was to characterise the putative analgesic

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