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EHU094851

Sigma-Aldrich

MISSION® esiRNA

targeting human APBB3

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51
Pricing and availability is not currently available.

description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CAAGTGCCATGTGTTTTGCTGTGATGTCCCTGCCAAGGCCATTGCCAGTGCCCTACATGGGCTTTGTGCCCAGATCTTGTCAGAGCGAGTAGAGGTCAGTGGTGATGCCTCTTGCTGCTCCCCAGACCCCATCTCTCCTGAAGACCTGCCACGGCAAGTGGAGCTGCTGGATGCGGTAAGCCAAGCTGCTCAGAAGTACGAGGCACTGTATATGGGGACACTGCCAGTCACCAAGGCCATGGGCATGGATGTGCTGAACGAGGCCATTGGTACCCTCACCGCCAGGGGGGACCGGAATGCCTGGGTCCCCACCATGCTCAGTGTGTCTGACTCTCTCATGACTGCACACCC

Ensembl | human accession no.

ENSG00000113108

NCBI accession no.

NM_006051

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... APBB3(10307) , APBB3(10307)

General description

MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Patompon Wongtrakoongate et al.
PLoS genetics, 11(10), e1005615-e1005615 (2015-10-27)
Long non-coding RNAs (lncRNAs) have been recognized as key players in transcriptional regulation. We show that the lncRNA steroid receptor RNA activator (SRA) participates in regulation through complex formation with trithorax group (TrxG) and polycomb repressive complex 2 (PRC2) complexes.

Questions

  1. What is the amount of 20 ug esiRNA in term mol?

    1 answer

    1. esiRNA is a pooled product with a variable molecular weight. The molecular weight can be estimated using the following information:
      - Calculation of esiRNA molar mass
      - A high percentage of the esiRNA pool is 21 bp
      - The average molar mass of one base including sugar and phosphate is 345 g/mol.
      - For an esiRNA (always double stranded) of 21 bp, the average molar mass can be calculated as follows: 2 x 21 x 345 = 14,490 g/mol

      For additional information please refer to the esiRNA technical bulletin in the link below:
      https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/786/318/cstesirnabul.pdf

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