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EHU005831

MISSION^® esiRNA

Name: MISSION<SUP>®</SUP> esiRNA
Brand: SIGMA

targeting human BMP5

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About This Item

UNSPSC Code:

41105324

NACRES:

NA.51

description

product line

MISSION^®

form

lyophilized powder

esiRNA cDNA target sequence

TATTTGTGCCTGCTGGAGGTGGAATTAACAGTAAGAAGGAGAAAGGGATTGAATGGACTTACAGGAAGGATTTCAAGTAAATTCAGGGAAACACATTTACTTGAATAGTACAACCTAGAGTATTATTTTACACTAAGACGACACAAAAGATGTTAAAGTTATCACCAAGCTGCCGGACAGATATATATTCCAACACCAAGGTGCAGATCAGCATAGATCTGTGATTCAGAAATCAGGATTTGTTTTGGAAAGAGCTCAAGGGTTGAGAAGAACTCAAAAGCAAGTGAAGATTACTTTGGGAACTACAGTTTATCAGAAGATCAACTTTTGCTAATTCAAATACCAAAGGCCTGATTATCATAAATTCATATAGGAATGCATAGGTCATCTGATCAAATAATATTAGCCGTCTTCTGCTACATCAATGCAGCAAAAACTCTTAACAACTGTGGATAATTGGAAATCTGAGTTTCAGCTTTCTTAGAAATAACTACTCTTGACATATTCCAAAATATTTAAAATAGGACAGGAAAATCGGTGAGGA

Ensembl | human accession no.

ENSG00000112175

NCBI accession no.

NM_021073

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... BMP5(653) , BMP5(653)

Related Categories

MISSION® esiRNA

General description

MISSION^® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Expression of GATA3 in MDA-MB-231 triple-negative breast cancer cells induces a growth inhibitory response to TGFß.

Isabel M Chu et al.

PloS one, 8(4), e61125-e61125 (2013-04-12)

Transforming growth factor (ß1TGFß1) can promote proliferation in late stage cancers but acts as a tumor suppressor in normal epithelial cells and in early stage cancers. Although, the TGFß pathway has been shown to play a key role in tumorigenesis

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