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E2006

Sigma-Aldrich

[D-Ala2]-Methionine enkephalinamide acetate salt

≥97% (HPLC)

Synonym(s):

Tyr-D-Ala-Gly-Phe-Met-NH2

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About This Item

Empirical Formula (Hill Notation):
C28H38N6O6S
CAS Number:
100929-50-8
Molecular Weight:
586.70
MDL number:
MFCD00133955
UNSPSC Code:
12352200
PubChem Substance ID:
329799024

Assay

≥97% (HPLC)

storage temp.

−20°C

SMILES string

CC(O)=O.CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(N)=O

InChI

1S/C28H38N6O6S.C2H4O2/c1-17(32-27(39)21(29)14-19-8-10-20(35)11-9-19)26(38)31-16-24(36)33-23(15-18-6-4-3-5-7-18)28(40)34-22(25(30)37)12-13-41-2;1-2(3)4/h3-11,17,21-23,35H,12-16,29H2,1-2H3,(H2,30,37)(H,31,38)(H,32,39)(H,33,36)(H,34,40);1H3,(H,3,4)/t17-,21+,22+,23+;/m1./s1

InChI key

CGDQCNFNHZVTLN-AUTZVVGKSA-N

Other Notes

Potent methionine enkephalin analog; resistant to enzymatic degradation

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
093H58113
093H58112

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C B Pert et al.
Science (New York, N.Y.), 194(4262), 330-332 (1976-10-15)
[D-Ala2]-Met-enkephalinamide (DALA), a synthetic enkephalin analog designed by in vitro analysis, binds to opiate receptors almost as tightly as methionine-enkephalin. Since it is not susceptible to degradation by brain enzymes, low doses (5 to 10 micrograms) cause profound, long-lasting, morphine-like

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