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Key Documents

C7628

Sigma-Aldrich

5β-Cholanic acid

≥99% (TLC)

Synonym(s):

Ursocholanic acid

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About This Item

Empirical Formula (Hill Notation):
C24H40O2
CAS Number:
Molecular Weight:
360.57
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.77
Pricing and availability is not currently available.

Quality Level

Assay

≥99% (TLC)

form

powder

SMILES string

[H]C12CCCCC1(C)C3CCC4(C)C(CCC4C3CC2)[C@@H](C)CCC(O)=O

InChI

1S/C24H40O2/c1-16(7-12-22(25)26)19-10-11-20-18-9-8-17-6-4-5-14-23(17,2)21(18)13-15-24(19,20)3/h16-21H,4-15H2,1-3H3,(H,25,26)

InChI key

RPKLZQLYODPWTM-UHFFFAOYSA-N

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Kyeongsoon Park et al.
Journal of controlled release : official journal of the Controlled Release Society, 122(3), 305-314 (2007-07-24)
To improve the in vivo tumor targeting characteristics of polymeric nanoparticles, three glycol chitosan (GC-20 kDa, GC-100 kDa, and GC-250 kDa) derivatives with different molecular weights were modified with cholanic acid at the same molar ratio. The resulting amphiphilic glycol
Jin Hee Na et al.
Journal of controlled release : official journal of the Controlled Release Society, 163(1), 2-9 (2012-08-01)
To evaluate the tumor targeting efficiency of self-assembled polymeric nanoparticles, four glycol chitosan nanoparticles (CNPs) with different degrees of hydrophobic substitution were prepared by coupling 7.5, 12, 23, and 35 wt.% of 5β-cholanic acid to hydrophilic glycol chitosan polymer (GC).
Nathan A Ledeboer et al.
Journal of bacteriology, 187(9), 3214-3226 (2005-04-20)
Recently, we demonstrated that Salmonella enterica serovar Typhimurium can form biofilm on HEp-2 cells in a type 1 fimbria-dependent manner. Previous work on Salmonella exopolysaccharide (EPS) in biofilm indicated that the EPS composition can vary based upon the substratum on
Jae Hyung Park et al.
Journal of controlled release : official journal of the Controlled Release Society, 95(3), 579-588 (2004-03-17)
The synthetic peptide bearing Arg-Gly-Asp (RGD) sequence is considered to specifically bind to alpha(v)beta(3) integrin expressed on endothelial cells in the angiogenic blood vessels, which provides a potential to inhibit the tumor growth. As a carrier for the RGD peptide
Allan D Heibein et al.
BMC cancer, 12, 381-381 (2012-09-04)
Since proteins involved in chemotherapy drug pharmacokinetics and pharmacodynamics have a strong impact on the uptake, metabolism, and efflux of such drugs, they likely play critical roles in resistance to chemotherapy drugs in cancer patients. To investigate this hypothesis, we

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