AV30228

Anti-TERF2 antibody produced in rabbit

IgG fraction of antiserum

• Synonym(s): Anti-TRBF2, Anti-TRF2, Anti-Telomeric repeat binding factor 2
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: IgG fraction of antiserum
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: 55 kDa
• species reactivity: mouse, human, bovine, dog, rabbit, guinea pig, horse, rat
• concentration: 0.5 mg - 1 mg/mL
• technique(s): western blot: suitable
• NCBI accession no.: NP_005643
• UniProt accession no.: Q15554
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... TERF2(7014)

Description

General description

TERF2 is a telomeric protein that forms a part of the telomere nucleoprotein complex. TERF2 is known to regulate the length of telomeres and is also known to protect telomeres.
Rabbit Anti-TERF2 antibody recognizes human, mouse, rat, bovine, and canine TERF2.

Immunogen

Synthetic peptide directed towards the C terminal region of human TERF2

Application

Rabbit Anti-TERF2 antibody is suitable for use in western blot at a concentration of 5.0μg/ml.

Biochem/physiol Actions

TERF2 is a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Sequence

Synthetic peptide located within the following region: TVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAVMIKDRWRTMKRLGMN

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable