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A1501

Sigma-Aldrich

N-Acetyl-D-methionine

~99%, suitable for ligand binding assays

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About This Item

Empirical Formula (Hill Notation):
C7H13NO3S
CAS Number:
1509-92-8
Molecular Weight:
191.25
Beilstein:
1725553
EC Number:
216-144-4
MDL number:
MFCD00069962
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
24890549
NACRES:
NA.26

product name

N-Acetyl-D-methionine, ~99%

Assay

~99%

form

powder or crystals

technique(s)

ligand binding assay: suitable

color

white

mp

102.3-103.6 °C

storage temp.

−20°C

SMILES string

CSCC[C@@H](NC(C)=O)C(O)=O

InChI

1S/C7H13NO3S/c1-5(9)8-6(7(10)11)3-4-12-2/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)/t6-/m1/s1

InChI key

XUYPXLNMDZIRQH-ZCFIWIBFSA-N

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Application

N-Acetyl-D-methionine may be used as a substrate to identify, differentiate and characterized N-acylamino acid racemase(s) and N-acyl-D-amino acid amidohydrolase(s).

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Pei-Hsun Lin et al.
European journal of biochemistry, 269(19), 4868-4878 (2002-10-02)
An N-acyl-d-amino acid amidohydrolase (N-D-AAase) was identified in cell extracts of a strain, Iso1, isolated from an environment containing N-acetyl-d-methionine. The bacterium was classified as Variovorax paradoxus by phylogenetic analysis. The gene was cloned and sequenced. The gene consisted of
Wen-Ching Wang et al.
Journal of molecular biology, 342(1), 155-169 (2004-08-18)
N-acylamino acid racemase (NAAAR) catalyzes the racemization of N-acylamino acids and can be used in concert with an aminoacylase to produce enantiopure alpha-amino acids, a process that has potential industrial applications. Here we have cloned and characterized an NAAAR homologue
R M Millis et al.
Nutrition and cancer, 31(1), 49-55 (1998-07-31)
Previous studies have shown that alteration of the dietary arginine-methionine balance by use of synthetic L-amino acids inhibits tumor growth of a subcutaneously transplanted Morris hepatoma at the expense of maintaining body weight. However, L-methionine is susceptible to degradation and
K Lertratanangkoon et al.
Toxicology and applied pharmacology, 122(2), 191-199 (1993-10-01)
Bromobenzene (800 mg/kg, ip) caused severe liver necrosis with massive hemorrhage in the golden Syrian hamster within the first 24 hr. Kidney injury was also observed. Treatment with N-acetylmethionine (NAM) at an ip dose of 1200 mg/kg at 5 hr
Kevin M Williams et al.
Journal of inorganic biochemistry, 99(11), 2119-2126 (2005-09-01)
The reaction of N-acetylmethionine (N-AcMet) with the complex [Pt(Et(2)en)(D(2)O)(2)](2+) (Et(2)en=N,N-diethylethylenediamine) was studied by NMR spectroscopy and molecular mechanics calculations. Complexes containing two methionine residues coordinated to the platinum atom were calculated to be relatively high in energy unless the bulk
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