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Nifuroxazide

VETRANAL®, analytical standard

Synonym(s):

5-Nitro-2-furaldehyde p-hydroxybenzoylhydrazone

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About This Item

Empirical Formula (Hill Notation):
C12H9N3O5
CAS Number:
965-52-6
Molecular Weight:
275.22
Beilstein:
4264976
EC Number:
213-522-0
MDL number:
MFCD00079482
UNSPSC Code:
41116107
PubChem Substance ID:
329757202
NACRES:
NA.24

grade

analytical standard

Quality Level

200

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

SMILES string

Oc1ccc(cc1)C(=O)N\N=C\c2ccc(o2)[N+]([O-])=O

InChI

1S/C12H9N3O5/c16-9-3-1-8(2-4-9)12(17)14-13-7-10-5-6-11(20-10)15(18)19/h1-7,16H,(H,14,17)/b13-7+

InChI key

YCWSUKQGVSGXJO-NTUHNPAUSA-N

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General description

Nifuroxazide is an oral antibiotic, which may be used for the treatment of diarrhea.

Application

Nifuroxazide may be used as a reference standard in the determination of the analyte in plasma samples using high-performance liquid chromatography (HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCK3952
BCCF2302
BCBW4413
BCBW1543
SZBC354XV

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Bernard G Cipolla et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 64(5), 363-368 (2010-01-29)
Reducing polyamine uptake by selecting low polyamine-containing foodstuffs and reducing bacterial gut production can improve performance status and pain control in hormone refractory prostate cancer (HRPC) patients. Long term PRD observance and tolerance were assessed. Cancer specific survival was studied
Fadia H Metwally
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 69(2), 343-349 (2007-07-17)
The quantitative predictive abilities of the new and simple bivariate spectrophotometric method are compared with the results obtained by the use of multivariate calibration methods [the classical least squares (CLS), principle component regression (PCR) and partial least squares (PLS)], using
Rebai Ben Ammar et al.
Chemico-biological interactions, 174(1), 1-10 (2008-05-31)
The effect of extracts obtained from Rhamnus alaternus L. leaves on genotoxicity and SOS response induced by aflatoxin B(1) (10 microg/assay) as well as nifuroxazide (20 microg/assay) was investigated in a bacterial assay system, i.e., the SOS chromotest with Escherichia
Fávero Reisdorfer Paula et al.
Bioorganic & medicinal chemistry, 17(7), 2673-2679 (2009-03-24)
In this study, in vitro anti-T. cruzi activity assays of nifuroxazide (NX) analogues, such as 5-nitro-2-furfuryliden and 5-nitro-2-theniliden derivatives, were performed. A molecular modeling approach was also carried out to relate the lipophilicity potential (LP) property and biological activity data.
Philippe Quillardet et al.
Mutagenesis, 21(5), 305-311 (2006-08-10)
Nitrofurans are widely used in human medicine, as nitrofurantoin and nifuroxazide, still prescribed for long-term antimicrobial prophylaxis of urinary tract and gastrointestinal infection in humans respectively. Recent experiments in mammals, as well as reports mentioning toxic effects in humans associated
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