AB1248
Anti-Cytochrome P450 Enzyme CYP1A2 Antibody
serum, Chemicon®
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About This Item
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biological source
rabbit
Quality Level
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... CYP1A2(1544)
Specificity
Reacts with human cytochrome P450 enzyme CYP1A2 in hepatic microsomal fraction. No cross-reactivity with other cytochrome P450 enzymes. By Western blot the antibody recognizes a protein with a molecular weight of approximately 54 kDa.
Immunogen
Synthetic peptide
Application
Anti-Cytochrome P450 Enzyme CYP1A2 Antibody is an antibody against Cytochrome P450 Enzyme CYP1A2 for use in IH & WB.
Research Category
Metabolism
Metabolism
Research Sub Category
Enzymes & Biochemistry
Enzymes & Biochemistry
Western blot: 1:1,000-1:4,000
Immunohistochemistry on frozen and formaldehyde treated sections.
Optimal working dilutions must be determined by end user.
Immunohistochemistry on frozen and formaldehyde treated sections.
Optimal working dilutions must be determined by end user.
Linkage
Replaces: MAB3526
Physical form
Rabbit antiserum. Liquid. No preservatives
Storage and Stability
Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Frontiers in physiology, 7, 548-548 (2016-12-03)
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Medical science monitor : international medical journal of experimental and clinical research, 26, e922149-e922149 (2020-04-15)
BACKGROUND Leonurine is an active component of the traditional Chinese medicine Leonurus japonicus. This study aimed to investigate the effects of overexpressed CYP450s on the metabolic activity of leonurine. MATERIAL AND METHODS BEAS-2B cells stably expressing CYP1A1, 1A2, 2A13, 2B6
Skin pharmacology and physiology, 23(1), 29-39 (2010-01-22)
Organotypic skin models are frequently used for a wide range of applications and latterly also for dermatotoxicological studies. To evaluate their practicability for the investigation of xenobiotic metabolism in human skin we compared three types of organotypic skin models, acquired
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