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870715P

Avanti

15:0 Coenzyme A

Avanti Research™ - A Croda Brand 870715P, powder

Synonym(s):

pentadecanoyl Coenzyme A (ammonium salt)

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About This Item

Empirical Formula (Hill Notation):
C36H73N10O17P3S
CAS Number:
24870-39-1
Molecular Weight:
1043.01
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 5 mg (870715P-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 870715P

application(s)

lipidomics

lipid type

coenzymes

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@@](C(NCCC(NCCSC(CCCCCCCCCCCCCC)=O)=O)=O)(C(C)(COP([O-])(OP([O-])(OC[C@H]([C@H]1OP([O-])(O)=O)O[C@H]([C@@H]1O)N2C3=C(C(N)=NC=N3)N=C2)=O)=O)C)[H].[NH4+].[NH4+].[NH4+]

General description

15:0 Coenzyme A, also known as pentadecanoyl Coenzyme A, is a coenzyme A derivative of pentadecanoic acid. 15:0 Coenzyme A is a long-chain acyl CoA and the product of the first round of β-oxidation. It is a substrate for serine palmitoyltransferase (SPT) for de novo synthesis of C17-long chain bases.

Application

15:0 Coenzyme A has been used as a constituent of reaction cocktail in microsomal serine palmitoyltransferase (SPT) assay.

Packaging

5 mL Amber Glass Screw Cap Vial (870715P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Use of isotopically labeled substrates reveals kinetic differences between human and bacterial serine palmitoyltransferase
Harrison PJ, et al.
Journal of Lipid Research, 60(5), 953-962 (2019)
Peter J Harrison et al.
Journal of lipid research, 60(5), 953-962 (2019-02-23)
Isotope labels are frequently used tools to track metabolites through complex biochemical pathways and to discern the mechanisms of enzyme-catalyzed reactions. Isotopically labeled l-serine is often used to monitor the activity of the first enzyme in sphingolipid biosynthesis, serine palmitoyltransferase
Analysis of coenzyme A activated compounds in actinomycetes
Cabruja M, et al.
Applied Microbiology and Biotechnology, 100(16), 7239-7248 (2016)
Matías Cabruja et al.
Applied microbiology and biotechnology, 100(16), 7239-7248 (2016-06-09)
Acyl-CoAs are crucial compounds involved in essential metabolic pathways such as the Krebs cycle and lipid, carbohydrate, and amino acid metabolisms, and they are also key signal molecules involved in the transcriptional regulation of lipid biosynthesis in many organisms. In

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