860520P

C20 Ceramide (d18:1/20:0)

Avanti Research^™ - A Croda Brand 860520P, powder

• Synonym(s): N-arachidoyl-D-erythro-sphingosine
• Empirical Formula (Hill Notation): C₃₈H₇₅NO₃
• CAS Number: 123482-93-9
• Molecular Weight: 594.01
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• form: powder
• packaging: pkg of 1 × 5 mg (860520P-5mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 860520P
• lipid type: sphingolipids
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: OC[C@]([H])(NC(CCCCCCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC
• InChI: 1S/C38H75NO3/c1-3-5-7-9-11-13-15-17-18-19-20-22-24-26-28-30-32-34-38(42)39-36(35-40)37(41)33-31-29-27-25-23-21-16-14-12-10-8-6-4-2/h31,33,36-37,40-41H,3-30,32,34-35H2,1-2H3,(H,39,42)/b33-31+/t36-,37+/m0/s1
• InChI key: XWBWIAOWSABHFI-NUKVNZTCSA-N

Description

General description

C20 Ceramide (d18:1/20:0) or N-arachidoyl-D-erythro-sphingosine is a synthetic ceramide containing sphingosine with arachidonic acid. Ceramide synthase 2 is responsible for the synthesis of C20 ceramide.

Application

C20 Ceramide (d18:1/20:0) has been used:

• as a standard to quantify ceramide content in muscle tissue samples using high-performance liquid chromatography/tandem mass spectrometry (LC/MS2)
• as a standard for the quantitation of sphingolipid metabolites
• to study its effects on mitochondrial-to-cytosolic stress response (MCSR) induction

Biochem/physiol Actions

Altered levels of C20 ceramide might function as a potential biomarker for monitoring tumor.

Packaging

5 mL Amber Glass Screw Cap Vial (860520P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids