Skip to Content
Merck
All Photos(1)

Documents

D152803

Sigma-Aldrich

Dimethylcarbamyl chloride

98%

Synonym(s):

Chloroformic acid dimethyl amide, Dimethylcarbamoyl chloride

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
(CH3)2NCOCl
CAS Number:
79-44-7
Molecular Weight:
107.54
Beilstein:
878197
EC Number:
201-208-6
MDL number:
MFCD00000635
UNSPSC Code:
12352100
PubChem Substance ID:
24893469
NACRES:
NA.22

Assay

98%

form

liquid

refractive index

n20/D 1.453 (lit.)

bp

167-168 °C/775 mmHg (lit.)

mp

−33 °C (lit.)

density

1.168 g/mL at 25 °C (lit.)

SMILES string

CN(C)C(Cl)=O

InChI

1S/C3H6ClNO/c1-5(2)3(4)6/h1-2H3

InChI key

YIIMEMSDCNDGTB-UHFFFAOYSA-N

Related Categories

Application

Dimethylcarbamyl chloride can be used to synthesize:
  • Disubstituted carbamates from benzylphenols.
  • 2-Cyanoisonicotinamide by reacting with isonicotinic acid N-oxide and zinc cyanide. This method was adopted to synthesize a novel xanthine oxidoreductase inhibitor.
  • Acetylcholinesterase (AChE) and serotonin transporter (SERT) dual inhibitors.

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

179.6 °F - closed cup

Flash Point(C)

82 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Design and synthesis of dual inhibitors of acetylcholinesterase and serotonin transporter targeting potential agents for Alzheimer's disease.
Kogen H, et al.
Organic Letters, 4(20), 3359-3362 (2002)
A E Hochwalt et al.
Molecular carcinogenesis, 1(1), 4-6 (1988-01-01)
Rat nasal squamous cell carcinomas induced by inhalation of three direct-acting alkylating agents yielded DNA containing activated oncogenes with no homology to any member of the ras family. The novel NIH 3T3 transforming oncogenes from tumors induced by beta-propiolactone and
C A Snyder et al.
Archives of toxicology, 61(1), 3-6 (1987-01-01)
A new inhalation exposure system has been developed which allows the determination of inhaled doses of vapors and gases by laboratory rats. The system consists of saran bags connected to head-only exposure cylinders via one-way valves. One bag serves as
G Sonnenfeld et al.
Journal of interferon research, 4(1), 129-133 (1984-01-01)
Several carcinogens have been shown to depress in vitro interferon (IFN) induction, while closely matched weakly or noncarcinogenic analogues had no effect on IFN induction. In this study, specific carcinogens that were difficult to detect by the Ames Salmonella assay
Dimethylcarbamoyl chloride.
Report on carcinogens : carcinogen profiles, 10, 106-107 (2004-08-25)
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service