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A5877

Sigma-Aldrich

Adrenochrome semicarbazone

Synonym(s):

2-(1,2,3,6-tetrahydro-3-hydroxy-1-methyl-6-oxoindol-5-ylidene)-hydrazinecarboxamide, 3-Hydroxy-1-methyl-5,6-indolindione-5-semicarbazone, Adrenochrome monosemicarbazone, Carbazochrome, NSC 73742

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About This Item

Empirical Formula (Hill Notation):
C10H12N4O3
CAS Number:
69-81-8
Molecular Weight:
236.23
EC Number:
200-717-0
MDL number:
MFCD00130253
UNSPSC Code:
12352100
PubChem Substance ID:
57653863

storage temp.

−20°C

SMILES string

CN1CC(O)C2=C\C(=N/NC(N)=O)C(=O)C=C12

InChI

1S/C10H12N4O3/c1-14-4-9(16)5-2-6(12-13-10(11)17)8(15)3-7(5)14/h2-3,9,16H,4H2,1H3,(H3,11,13,17)/b12-6+

InChI key

XSXCZNVKFKNLPR-WUXMJOGZSA-N

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
093F05631
017C0226

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Yasunori Miyazaki et al.
Chemical & pharmaceutical bulletin, 64(12), 1698-1706 (2016-12-03)
Scientific approaches for dispensation are important for the quality and efficacy of drug treatments. Therefore, for the dispensation of powdered medicines, we have developed a powder blending method using a planetary centrifugal mixer (PCM) to replace the empirical manual method
S Tassniyom et al.
The Journal of pediatrics, 131(4), 525-528 (1997-12-05)
We studied the ability of carbazochrome sodium sulfonate (AC-17) to prevent capillary permeability in dengue hemorrhagic fever/dengue shock syndrome. A randomized, placebo-controlled trial in 95 children stratified by age and sex was conducted in two hospitals during 1992. AC-17 (n
Y Hoshino et al.
Internal medicine (Tokyo, Japan), 32(11), 879-881 (1993-11-01)
A 55-year-old woman, who had systemic amyloidosis associated with multiple myeloma, had sudden development of hematomas of her lip and upper eye lid. There was no evidence of deterioration of multiple myeloma, thrombocytopenia nor deficiency of coagulation factors. Biopsy specimen
Effects of carbazochrome sodium sulfonate (AC-17) on oleic acid-induced lung injury.
H Moriuchi et al.
Pharmacology & toxicology, 77(3), 238-240 (1995-09-01)
Y Matsumoto et al.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 6(3), 233-238 (1995-05-01)
This study investigated the effect of carbazochrome sodium sulphonate (AC-17) on the accumulation of tissue-type plasminogen activator antigen (t-PA:Ag) and plasminogen activator inhibitor-1 antigen (PAI-1:Ag) in culture medium of human umbilical vein endothelial cells (HUVEC). HUVEC were cultured in the
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