Journal of pharmaceutical sciences, 97(1), 225-236 (2007-08-28)
Treatment of systemic disease with phosphorothioate antisense oligonucleotides (PS ASOs) has been accomplished using local or parenteral routes of administration to date. This report describes, for the first time, the effective oral delivery of a second generation oligonucleotide where significant
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 8(3), 193-201 (1999-06-24)
The effect of the neutron activation factors, i.e., admixture of samarium oxide (Sm2O3) and irradiation time, on the physico-chemical properties of the raw materials and the in vitro dissolution and disintegration of hydrophilic and lipophilic suppositories was investigated. It was
Journal of biomedical materials research. Part A, 94(1), 130-136 (2010-02-04)
The biocompatibility of natural samarium (III) oxide, which has previously been used for treatment in bone-related diseases was determined as a first step in its evaluation as a bone implant material. Assessment for 28 days using osteoblast-like cells revealed no
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 67(1), 46-49 (2008-08-19)
Cross sections of the (147)Sm(n, alpha)(144)Nd reaction were measured at En=5.0 and 6.0MeV. A twin gridded ionization chamber was used as a charged particle detector and two large area (147)Sm(2)O(3) samples placed back to back were employed. Experiments were performed
To develop a robust radiolabeling technique to enable evaluation of difficult to radiolabel gastric retentive formulations using gamma scintigraphy. The use of a successful radiolabel will allow accurate assessment of the gastric residence time of the formulations. The retention of
Magnetic materials find diverse applications from data storage to renewable energy.
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