305855

(3-(Dimethylamino)propyl)triphenylphosphonium bromide

98%

• Linear Formula: (CH₃)₂NCH₂CH₂CH₂P(C₆H₅)₃(Br)
• CAS Number: 18355-96-9
• Molecular Weight: 428.34
• Beilstein: 4637548
• MDL number: MFCD00012200
• UNSPSC Code: 12352116
• PubChem Substance ID: 24858461

Properties

• Assay: 98%
• reaction suitability: reaction type: C-C Bond Formation
• mp: 193-196 °C
• SMILES string: [Br-].CN(C)CCC[P+](c1ccccc1)(c2ccccc2)c3ccccc3
• InChI: 1S/C23H27NP.BrH/c1-24(2)19-12-20-25(21-13-6-3-7-14-21,22-15-8-4-9-16-22)23-17-10-5-11-18-23;/h3-11,13-18H,12,19-20H2,1-2H3;1H/q+1;/p-1
• InChI key: SSWPSKSQQSJKKF-UHFFFAOYSA-M

Description

Application

Reactant for preparation of:

• Topoisomerase I-targeting antitumor agents
• C15-C21 stereopentad of discodermolide via cleavage of aminoglycosides, double-bond isomerization, and selective hydroxyl group protection
• Diphenyl amine based sodium channel blockers, effective against hNav1.2

• Reactant for Wittig reaction with benzaldehyde

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves