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291161

Sigma-Aldrich

4,7,13,16,21-Pentaoxa-1,10-diazabicyclo[8.8.5]tricosane

98%

Synonym(s):

Kryptofix® 221

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About This Item

Empirical Formula (Hill Notation):
C16H32N2O5
CAS Number:
Molecular Weight:
332.44
Beilstein:
616444
EC Number:
MDL number:
UNSPSC Code:
12352005
PubChem Substance ID:
NACRES:
NA.22

Assay

98%

refractive index

n20/D 1.5018 (lit.)

density

1.111 g/mL at 20 °C (lit.)

SMILES string

C1COCCN2CCOCCOCCN(CCO1)CCOCC2

InChI

1S/C16H32N2O5/c1-7-19-8-2-18-5-11-22-15-13-20-9-3-17(1)4-10-21-14-16-23-12-6-18/h1-16H2

InChI key

HDLXPNDSLDLJHF-UHFFFAOYSA-N

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Application

4,7,13,16,21-Pentaoxa-1,10-diazabicyclo[8.8.5]tricosane is a cryptand which is capable of forming complexes with metal cations. It is used to bind or trap cationic guests such as Na+, Cd2+, Zn2+ and Eu3+.

Legal Information

Kryptofix is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The kinetics of Na+ and K+ transport across the membrane of large unilamellar vesicles (LUV) were determined at two pH's when transport was induced by (221)C10-cryptand (diaza-1,10-decyl-5-pentaoxa-4,7,13,16,21-bicyclo [8.8.5.] tricosane) at various temperatures, and by nonactin at 25 degrees C and

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