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283967

Sigma-Aldrich

DL-2-Amino-5-phosphonovaleric acid

98%

Synonym(s):

5-Phosphono-DL-norvaline, DL-5-Phosphononorvaline, APV

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About This Item

Empirical Formula (Hill Notation):
C5H12NO5P
CAS Number:
Molecular Weight:
197.13
Beilstein:
2446389
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

Assay

98%

form

solid

SMILES string

NC(CCCP(O)(O)=O)C(O)=O

InChI

1S/C5H12NO5P/c6-4(5(7)8)2-1-3-12(9,10)11/h4H,1-3,6H2,(H,7,8)(H2,9,10,11)

InChI key

VOROEQBFPPIACJ-UHFFFAOYSA-N


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Thomas Mager et al.
Nature communications, 9(1), 1750-1750 (2018-05-03)
Optogenetics revolutionizes basic research in neuroscience and cell biology and bears potential for medical applications. We develop mutants leading to a unifying concept for the construction of various channelrhodopsins with fast closing kinetics. Due to different absorption maxima these channelrhodopsins
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Aging, 11(14), 5140-5157 (2019-07-25)
We examined the contribution of N-methyl-D-aspartate receptor (NMDAR) subunits in the redox-mediated decline in NMDAR function during aging. GluN2A and GluN2B selective antagonists decreased peak NMDAR currents to a similar extent in young and aged animals, indicating that a shift
Emily A Ferenczi et al.
Scientific reports, 6, 23947-23947 (2016-04-06)
The extracellular ionic environment in neural tissue has the capacity to influence, and be influenced by, natural bouts of neural activity. We employed optogenetic approaches to control and investigate these interactions within and between cells, and across spatial scales. We
Ira Espuny-Camacho et al.
Neuron, 77(3), 440-456 (2013-02-12)
The study of human cortical development has major implications for brain evolution and diseases but has remained elusive due to paucity of experimental models. Here we found that human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), cultured
Giovanni Morelli et al.
Cerebral cortex (New York, N.Y. : 1991), 27(3), 1863-1877 (2016-02-20)
The development of the cerebral cortex is a complex process that requires the generation, migration, and differentiation of neurons. Interfering with any of these steps can impair the establishment of connectivity and, hence, function of the adult brain. Neurotransmitter receptors

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