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199524

Sigma-Aldrich

Chlorophenol Red

indicator grade

Synonym(s):

3′,3′-Dichlorophenolsulfonaphthalein

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About This Item

Empirical Formula (Hill Notation):
C19H12Cl2O5S
CAS Number:
Molecular Weight:
423.27
Beilstein:
354053
EC Number:
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

grade

indicator grade

form

powder, crystals or chunks

color

dark brown

pH

4.8-6.7, yellow to violet

solubility

95% ethanol: 10 mg/mL

λmax

572 nm

ε (extinction coefficient)

≥12000 at 295-301 nm in 0.1 M NaOH
≥45000 at 573-579 nm in 0.1 M NaOH
≥5000 at 368-374 nm in 0.1 M NaOH

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

Oc1ccc(cc1Cl)C2(OS(=O)(=O)c3ccccc23)c4ccc(O)c(Cl)c4

InChI

1S/C19H12Cl2O5S/c20-14-9-11(5-7-16(14)22)19(12-6-8-17(23)15(21)10-12)13-3-1-2-4-18(13)27(24,25)26-19/h1-10,22-23H

InChI key

WWAABJGNHFGXSJ-UHFFFAOYSA-N

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Biochem/physiol Actions

Chlorophenol red is a pH indicator. It is used as an optical transducer of acetyl cholinesterase inhibition by the analytes. Chlorophenol red is also used to selectively determine chlorine dioxide in drinking water. It has been used in the novel assay to detect transformed protoplast-derived Zea mays colonies on Phosphinothricin (PPT).

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Fiber optic monitoring of carbamate pesticides using porous glass with covalently bound chlorophenol red.
Xavier MP
Biosensors And Bioelectronics, 14, 895-905 (2000)
Riccardo Martini et al.
Chembiochem : a European journal of chemical biology, 18(4), 374-377 (2016-12-20)
In recent years many advances have been made in the fight against HIV-1 infection. However, the lack of a vaccine, together with the increasing resistance to the highly active anti-retroviral therapy (HAART), make HIV-1 infection still a serious global emergency.
M R Simões-Silva et al.
Biochemical pharmacology, 145, 46-53 (2017-09-06)
Metronidazole (Mtz) is a commercial broad-spectrum nitroimidazolic derivative with relevant antimicrobial activity and relative safety profile. Therefore, it is fair to consider Mtz a candidate for drug repurposing for other neglected conditions such as Chagas disease (CD), a parasitic pathology
Selection of transformed protoplast-derived Zea mays colonies with phosphinothricin and a novel assay using the pH indicator chlorophenol red
Kramer C
Planta, 190, 454-458 (1993)
Erin M O'Donoghue et al.
Plant physiology and biochemistry : PPB, 113, 208-221 (2017-03-04)
Galactose (Gal) is incorporated into cell wall polysaccharides as flowers open, but then is lost because of β-galactosidase activity as flowers mature and wilt. The significance of this for flower physiology resides in the role of galactan-containing polysaccharides in the

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