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Sigma-Aldrich

Hydroxypropyl cellulose

average Mw ~1,000,000, powder, 20 mesh particle size (99% through)

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About This Item

CAS Number:
9004-64-2
MDL number:
MFCD00132688
UNSPSC Code:
12162002
NACRES:
NA.23

description

biological oxygen demand (BOD) 14,000 ppm

form

powder

autoignition temp.

752 °F

mol wt

average Mw ~1,000,000

impurities

<5 wt. %

particle size

20 mesh (99% through)

pH

5.0-8.5

interfacial tension mineral oil

12.5 dyn/cm, 0.1 wt. % in H2O (vs. mineral oil)

viscosity

1,275-3,500 cP, 1 wt. % in H2O(25 °C, Brookfield, spindle #3) (30 rpm)(lit.)

solubility

H2O: insoluble (above 45 °C)
polar organic solvents: soluble

density

0.5 g/mL at 25 °C (lit.)

InChI

1S/C12H20N2/c1-5-12(13)11-7-6-10(14(3)4)8-9(11)2/h6-8,12H,5,13H2,1-4H3

InChI key

RRHXDYJWVYFMKV-UHFFFAOYSA-N

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Related Categories

Application

  • Thermo-responsive aqueous foams: Hydroxypropyl cellulose has been studied for its properties as a green polymer that can alter its solubility with temperature changes, making it suitable for responsive foam applications (Braunschweig, 2019).
  • Interaction mechanism in aqueous solutions: A study on the interaction between hydroxypropyl cellulose and water in solutions, focusing on the importance of polymer chain length in determining the physical properties of the solutions (Martin-Pastor and Stoyanov, 2020).
  • Corrosion inhibition: Hydroxypropyl cellulose has shown effectiveness as a corrosion inhibitor for aluminium in acidic environments, highlighting its potential in material science and engineering applications (Nwanonenyi et al., 2019).
  • Orally disintegrating films: This application involves the formulation design of hydroxypropyl cellulose films, aiming to enhance the delivery and dissolution profile of pharmaceuticals, making it significant in drug delivery and pharmaceutical sciences (Takeuchi et al., 2018).

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Catherine Boissier et al.
Journal of pharmaceutical sciences, 101(7), 2512-2522 (2012-04-28)
Nuclear magnetic resonance (NMR) cryoporometry and scanning electron microscopy (SEM) image analysis have been used to investigate the size and shape distribution of pores in pharmaceutical coatings. The coatings were made from a mixture of hydroxypropylcellulose (HPC) and ethylcellulose (EC).
Ashish Sarode et al.
AAPS PharmSciTech, 14(1), 151-159 (2012-12-20)
Hydroxypropylcellulose (HPC)-SL and -SSL, low-viscosity hydroxypropylcellulose polymers, are versatile pharmaceutical excipients. The utility of HPC polymers was assessed for both dissolution enhancement and sustained release of pharmaceutical drugs using various processing techniques. The BCS class II drugs carbamazepine (CBZ), hydrochlorthiazide
R Logan et al.
Drug development and industrial pharmacy, 38(11), 1394-1404 (2012-03-23)
Impeller speed was varied from 300 to 1500 rpm during the wet high shear granulation of a placebo formulation using a new vertical shaft PharmaMATRIX-1 granulator. The resulting granules were extensively analysed for differences caused by the varying impeller speed
Homendra Naorem et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 101, 67-73 (2012-10-27)
The formation constant of triiodide ions from iodine-iodide equilibrium in aqueous-organic solvent or polymer mixed media have been determined spectrophotometrically at three different temperatures 20, 30 and 40°C. The organic solvents chosen for the study are ethylene glycol, 2-methoxy ethanol
Alexandre Monteiro et al.
Drug development and industrial pharmacy, 39(2), 266-283 (2012-04-17)
Nanoparticles of BCS Class II drugs are produced in wet stirred media mills operating in batch or recirculation mode with the goal of resolving the poor water-solubility issue. Scant information is available regarding the continuous production of drug nanoparticles via
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