15525
Boc-Tyr-OSu
≥99.0% (N)
Synonym(s):
Boc-L-tyrosine hydroxysuccinimide ester
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About This Item
Empirical Formula (Hill Notation):
C18H22N2O7
CAS Number:
Molecular Weight:
378.38
Beilstein:
1557147
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
Assay
≥99.0% (N)
optical activity
[α]20/D −13±1°, c = 1% in dioxane
mp
~190 °C (dec.)
application(s)
peptide synthesis
storage temp.
−20°C
SMILES string
CC(C)(C)OC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)ON2C(=O)CCC2=O
InChI
1S/C18H22N2O7/c1-18(2,3)26-17(25)19-13(10-11-4-6-12(21)7-5-11)16(24)27-20-14(22)8-9-15(20)23/h4-7,13,21H,8-10H2,1-3H3,(H,19,25)/t13-/m0/s1
InChI key
NZUDTLHVKHXJJJ-ZDUSSCGKSA-N
Other Notes
Reagent used in a rapid method for iodotyrosylation of peptides.; This method is equal to that of Bolton-Hunter but has the additional advantage that the derivatized peptide is readily deblocked to form a radiolabelled product with the same net charge as the starting material
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Iodotyrosylation of peptides using tertiary-Butyloxycarbonyl-L-[125I]iodotyrosine N-hydroxysuccinimide ester.
R K Assoian et al.
Analytical biochemistry, 103(1), 70-76 (1980-03-15)
Patrick Neuberg et al.
International journal of pharmaceutics, 566, 141-148 (2019-05-28)
Small interfering RNAs (siRNAs) can down-regulate the expression of a target mRNA molecule in a sequence-specific manner, making them an attractive new class of drugs with broad potential for the treatment of diverse human diseases. Here, we report the synthesis
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