RBP3
retinol binding protein 3, interstitial
Synonyms:
D10S64, D10S65, D10S66, IRBP, RBPI, RP66
Species:
Human RBP3 (5949), Mouse Rbp3 (19661), Rat Rbp3 (24711), dog RBP3 (489084), cow RBP3 (281443), sheep RBP3 (101115179), domestic cat RBP3 (101091050), domestic guinea pig Rbp3 (100723349), chicken RBP3 (395553)
UniProtKB ID:
Gene ID:
- Human(5949) Summary: Interphotoreceptor retinol-binding protein is a large glycoprotein known to bind retinoids and found primarily in the interphotoreceptor matrix of the retina between the retinal pigment epithelium and the photoreceptor cells. It is thought to transport retinoids between the retinal pigment epithelium and the photoreceptors, a critical role in the visual process.The human IRBP gene is approximately 9.5 kbp in length and consists of four exons separated by three introns. The introns are 1.6-1.9 kbp long. The gene is transcribed by photoreceptor and retinoblastoma cells into an approximately 4.3-kilobase mRNA that is translated and processed into a glycosylated protein of 135,000 Da. The amino acid sequence of human IRBP can be divided into four contiguous homology domains with 33-38% identity, suggesting a series of gene duplication events. In the gene, the boundaries of these domains are not defined by exon-intron junctions, as might have been expected. The first three homology domains and part of the fourth are all encoded by the first large exon, which is 3,180 base pairs long. The remainder of the fourth domain is encoded in the last three exons, which are 191, 143, and approximately 740 base pairs long, respectively. [provided by RefSeq, Jul 2008]
- Mouse(19661) retinol binding protein 3, interstitial
- Rat(24711) retinol binding protein 3, interstitial
- dog(489084) retinol binding protein 3, interstitial
- cow(281443) retinol binding protein 3, interstitial
- sheep(101115179) retinol binding protein 3, interstitial
- domestic cat(101091050) retinol binding protein 3, interstitial
- domestic guinea pig(100723349) retinol binding protein 3, interstitial
- chicken(395553) retinol binding protein 3, interstitial
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-RBP3 antibody produced in mouse, clone 4F3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot