Skip to Content
Merck

LRP1

low density lipoprotein receptor-related protein 1

Synonyms:
A2MR, APOER, APR, CD91, IGFBP3R, LRP, LRP1A, TGFBR5
Species:
Human LRP1 (4035), Mouse Lrp1 (16971), Rat Lrp1 (299858), dog LRP1 (481124), cow LRP1 (533894), sheep LRP1 (101120656), chicken LRP1 (396170), domestic guinea pig Lrp1 (100726418), Domestic Rabbit LRP1 (100009571), Thale Cress LRP1 (831108) ...More
UniProtKB ID:
Q07954, Q2PP12, Q8IVG8
Gene ID:
  • Human(4035) Summary: The protein encoded by this gene is an endocytic receptor involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the A2M-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer patients. [provided by RefSeq, Jan 2010]
  • Mouse(16971) low density lipoprotein receptor-related protein 1
  • Rat(299858) low density lipoprotein receptor-related protein 1
  • dog(481124) low density lipoprotein receptor-related protein 1
  • cow(533894) low density lipoprotein receptor-related protein 1
  • sheep(101120656) low density lipoprotein receptor-related protein 1
  • chicken(396170) low density lipoprotein receptor-related protein 1
  • domestic guinea pig(100726418) low density lipoprotein receptor-related protein 1
  • Domestic Rabbit(100009571) low density lipoprotein receptor-related protein 1
  • Thale Cress(831108) lateral root primordium protein-like protein
  • fruit fly(35799) LDL receptor protein 1
  • naked mole-rat(101723541) low density lipoprotein receptor-related protein 1
  • domestic cat(101090780) low density lipoprotein receptor-related protein 1
  • Domestic Rabbit(100009547) low density lipoprotein receptor-related protein 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
MABS2253
Anti-LRP1 α-chain Antibody, clone 8G1, ,
Species Reactivity
human
Application
ELISA
immunocytochemistry
immunoprecipitation (IP)
western blot
SAB1300081
Anti-LRP1 (C-term) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
SAB5700883
Anti-LRP1 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot
L2420
Monoclonal Anti-LRP1 antibody produced in mouse, ~1.0 mg/mL, clone LRP1-11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
western blot
L2295
Anti-LRP1 (N-terminal) antibody produced in rabbit, ~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
western blot