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Supelco

SPME LC Fiber Probe, C18

df 45 μm(C18, pkg of 5 ea

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About This Item

UNSPSC Code:
41115724
NACRES:
NB.21

material

metal alloy fiber
plain red hub

needle size

22 ga

packaging

pkg of 5 ea

df

45 μm (C18)

technique(s)

solid phase microextraction (SPME): suitable

needle L

25 mm (1 in.)

matrix active group

C18 coating

application(s)

food and beverages

compatibility

for use with solvent desorption

separation technique

reversed phase

General description

The SPME-LC fiber probes are intended as single-use devices for the extraction of small molecules out of a fluid followed by solvent desorption and LC analysis.

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Barbara Bojko et al.
Analytica chimica acta, 803, 75-81 (2013-11-13)
Metabolomics and biomarkers discovery are an integral part of bioanalysis. However, untargeted tissue analysis remains as the bottleneck of such studies due to the invasiveness of sample collection, as well as the laborious and time-consuming sample preparation protocols. In the
Florin Marcel Musteata et al.
Journal of pharmaceutical and biomedical analysis, 47(4-5), 907-912 (2008-05-13)
Pharmacokinetic (PK) studies in rats typically involve removal of serial blood samples following dosing. This research illustrates the development of a fast in vivo microextraction technique that has the potential to partly replace current sampling techniques based on blood draws
Joanne Chung Yan Yeung et al.
Analytica chimica acta, 665(2), 160-166 (2010-04-27)
The success of in vivo solid phase microextraction (SPME) depends significantly on the selection of calibration method. Three kinetic in vivo SPME calibration methods are evaluated in this paper: (1) on-fibre standardization (OFS), (2) dominant pre-equilibrium desorption (DPED), and (3)
Xu Zhang et al.
Journal of chromatography. A, 1216(45), 7664-7669 (2009-09-22)
Solid-phase microextraction (SPME) has been demonstrated to be useful for in vivo sampling in pharmacokinetic studies. In this study, a single time-point kinetic calibration for in vivo dynamic monitoring was developed by simplification of the laborious multiple time-point kinetic calibration
Solid-Phase Microextraction. How Far are We from Clinical Practice?
Bojko, B., et al.
TrAC, Trends in Analytical Chemistry, 30 (9), 1505-1512 (2011)
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Bioanalysis with SPME

Biocompatible SPME devices employ C18 bonded porous silica sorbent particles, in a binder which resists fouling by biological matrix components

Rapid Determination of Protein Binding Affinity Using Solid Phase Microextraction

Accurate protein binding affinities were measured using bioSPME more rapidly than membrane dialysis (RED) techniques. Binding affinities correlated to the reference values.

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