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SRP6060

Sigma-Aldrich

LEFTY-I human

recombinant, expressed in HEK 293 cells, ≥90% (SDS-PAGE)

Synonym(s):

Left-right determination factor 1, Left-right determination factor B, Protein LEFTY-1, Protein LEFTY-B

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.32

biological source

human

recombinant

expressed in HEK 293 cells

Assay

≥90% (SDS-PAGE)

form

lyophilized

mol wt

38 kDa

packaging

pkg of 10 μg

NCBI accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... LEFTY1(10637)

General description

BioVision′s LEFTY-1 is expressed in human 293 cells as a monomeric glycoprotein with an apparent molecular mass of 38 kDa. This cytokine is produced in a human cell expression system with serum-free, chemically defined media. Production in human 293 cells offers authentic glycosylation, contributing to stability in cell growth media. Lefty proteins function as an antagonist of the Nodal Signaling pathway. Proper functioning of Lefty is crucial to the proper development of the heart, lungs, spleen, and liver.

Physical form

Lyophilized in 10 mM Tris-HCl, pH 7.4, 50 mM NaCl, 0.5% CHAPS.

Preparation Note

Centrifuge the vial prior to opening.

Reconstitution

Reconstitute in sterile water.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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