SAB4700767
Monoclonal Anti-HBV antigen HBsAg antibody produced in mouse
clone HB5, purified immunoglobulin, buffered aqueous solution
Synonym(s):
Hbsag Antibody, Hbsag Antibody - Monoclonal Anti-HBV antigen HBsAg antibody produced in mouse
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
Recommended Products
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
HB5, monoclonal
form
buffered aqueous solution
species reactivity
hepatitis B virus
concentration
1 mg/mL
technique(s)
ELISA: suitable
immunocytochemistry: suitable
isotype
IgG2a
shipped in
wet ice
storage temp.
2-8°C
General description
HBsAg is the surface antigen of HBV (hepatitis B virus). It is secreted in the form of pleomorphic particles, mostly spherical and partly filamentous. HBV is usually spread due to percutaneous or mucosal exposure to infected blood and other body fluids.
The antibody HB5 recognizes following Hepatitis B virus (HBV) subtypes: ayw2, ayw3, ayw4, ayr, adw2, adw4, adrq+, adrq-. Hepatitis B surface antigen (HBsAg) is a marker of infectivity.
Specificity of the antibody HB5 was verified by ELISA on panel of virus subtypes identified on International Workshop on HBsAg Subtypes (Paris, April 1975). The antibody HB5 does not cross-block with the antibody HB3.
Specificity of the antibody HB5 was verified by ELISA on panel of virus subtypes identified on International Workshop on HBsAg Subtypes (Paris, April 1975). The antibody HB5 does not cross-block with the antibody HB3.
Immunogen
Purified HbsAg from human plasma.
Application
Monoclonal Anti-HBV antigen HBsAg antibody has been used in quantitative assays.
Biochem/physiol Actions
HBsAg acts as a clinical marker and helps to specify acute or chronic infection. Presence of HBsAg indicates HBV infection. Overexpression of HBsAg is seen in infected hepatocytes.
Features and Benefits
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Physical form
Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Palashpriya Das et al.
World journal of hepatology, 12(10), 775-791 (2020-11-18)
The recent rise in the incidence of hepatitis B virus (HBV) infections in a densely populated city of eastern India ("mixing vessel" of people of varied socio-economic and immune status) prompted this study. Applying saliva on fingers for enumerating bank
Abinash Mallick et al.
Journal of medical virology, 96(6), e29771-e29771 (2024-06-27)
COVID-19 tended to be less aggressive in dengue endemic regions. Conversely, dengue cases plummeted in dengue endemic zones during the active years of the pandemic (2020-2021). We and others have demonstrated serological cross-reactivity between these two viruses of different families.
Establishment of magnetic microparticles-assisted time-resolved fluoroimmunoassay for determinating biomarker models in human serum.
Ren ZQ, et al.
PLoS ONE, 10(6), e0130481-e0130481 (2015)
Yunru Chen et al.
Journal of medical virology, 91(10), 1811-1817 (2019-06-19)
The safety and necessity of hepatitis B immunoglobulin (HBIG) in preventing the mother-to-child transmission of hepatitis B virus (HBV) are still controversial because of its unclear mechanism of action and the inconsistent injection programs used during gestation. This study aimed
Global epidemiology of hepatitis B virus infection: new estimates of age-specific HBsAg seroprevalence and endemicity.
Ott JJ, et al.
Vaccine, 30(12), 2212-2219 (2012)
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