SAB4300241

Anti-phospho-MAPKAPK2 (pThr³³⁴) antibody produced in rabbit

affinity isolated antibody

• Synonym(s): Anti-MK2 antibody produced in rabbit, Anti-mitogen-activated protein kinase-activated protein kinase 2 antibody produced in rabbit
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: ~49 kDa
• species reactivity: human, rat, mouse
• concentration: 1 mg/mL
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; indirect immunofluorescence: 1:100-1:200; western blot: 1:500-1:1000
• isotype: IgG
• immunogen sequence: (P-Q-TP-P-L)
• NCBI accession no.: NP_004750.1
• UniProt accession no.: P49137
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pThr334)
• Gene Information: human ... MAPKAPK2(9261)

Description

Immunogen

Peptide sequence around phosphorylation site of threonine 334 (P-Q-T(p)-P-L), according to the protein MAPKAPK2.

Features and Benefits

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Target description

MAPKAPK-2 encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable