RAB0051
Human PARC / CCL18 ELISA Kit
for serum, plasma, cell culture supernatant and urine
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About This Item
UNSPSC Code:
41116158
NACRES:
NA.32
Recommended Products
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
capture ELISA: suitable
input
sample type serum
sample type cell culture supernatant(s)
sample type plasma
sample type urine
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 2 pg/mL
standard curve range: 2.74-2000 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... CCL18(6362)
General description
CC chemokine ligand 18 (CCL18) is expressed at high levels in human lung and serum. This CC chemokine can be found in primates only. The CCL18 gene is mapped to the human chromosome 17q11.2.
The Human PARC ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human PARC in serum, plasma, cell culture supernatants and urine.
Immunogen
Recombinant Human PARC
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Biochem/physiol Actions
C-C motif chemokine ligand 18 (CCL18) has immunological functions and is associated with tumor progression. It is secreted by tumor associated macrophages (TAMs). The protein recruits naive T-cells and dendritic cells, and induces regulatory T-cells. It also acts as a chemokine for helper T lymphocytes and cytotoxic T lymphocytes. CCL18 has been implicated in the pathogenesis of many cancers.
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
Kit Components Also Available Separately
Product No.
Description
SDS
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Met. Corr. 1
Storage Class Code
8A - Combustible corrosive hazardous materials
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Shinichiro Ohshimo et al.
Respiratory medicine, 108(7), 1031-1039 (2014-05-20)
Acute exacerbation (AE) is a major cause of death in idiopathic pulmonary fibrosis (IPF). However, little is known about sensitive biomarkers for predicting AE. The aim of our study was to investigate the significance of KL-6 and CC-Chemokine Ligand 18
Local Concentrations of CC-Chemokine-Ligand 18 Correlate with Tumor Size in Non-small Cell Lung Cancer and Are Elevated in Lymph Node-positive Disease.
Schmid S
Anticancer Research (2016)
25th European Photovoltaic Solar Energy Conference and Exhibition / 5th World Conference on Photovoltaic Energy Conversion; 6-10 September 2010; Valencia; Spain; EU PVSEC Proceedings null
CCL18 from tumor-cells promotes epithelial ovarian cancer metastasis via mTOR signaling pathway
Qi Wang
Molecular Carcinogenesis (2016)
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