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M3387

N-Methyl-L-aspartic acid

Name: N-Methyl-<SC>L</SC>-aspartic acid
Brand: SIGMA

Synonym(s):

(S)-2-(Methylamino)succinic acid

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About This Item

Empirical Formula (Hill Notation):

C₅H₉NO₄

CAS Number:

4226-18-0

Molecular Weight:

147.13

Beilstein:

2437887

MDL number:

MFCD00069561

UNSPSC Code:

12352200

PubChem Substance ID:

24896836

form

powder

color

white

SMILES string

CN[C@@H](CC(O)=O)C(O)=O

InChI

1S/C5H9NO4/c1-6-3(5(9)10)2-4(7)8/h3,6H,2H2,1H3,(H,7,8)(H,9,10)/t3-/m0/s1

InChI key

HOKKHZGPKSLGJE-VKHMYHEASA-N

Gene Information

rat ... Gria1(50592) , Grik1(29559) , Grin2a(24409)

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Other Notes

Inactive isomer of N-methyl-D-aspartic acid (NMDA).

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Structure-function investigation of 3-methylaspartate ammonia lyase reveals substrate molecular determinants for the deamination reaction.

Veronica Saez-Jimenez et al.

PloS one, 15(5), e0233467-e0233467 (2020-05-22)

The enzymatic reactions leading to the deamination of β-lysine, lysine, or 2-aminoadipic acid are of great interest for the metabolic conversion of lysine to adipic acid. Enzymes able to carry out these reactions are not known, however ammonia lyases (EC

Watkins, J.C.

Journal of Medicinal and Pharmaceutical Chemistry, 5, 1187-1187 (1962)

Distinct preoptic-BST nuclei dissociate paternal and infanticidal behavior in mice.

Yousuke Tsuneoka et al.

The EMBO journal, 34(21), 2652-2670 (2015-10-02)

Paternal behavior is not innate but arises through social experience. After mating and becoming fathers, male mice change their behavior toward pups from infanticide to paternal care. However, the precise brain areas and circuit mechanisms connecting these social behaviors are

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