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Key Documents

D9006

Sigma-Aldrich

Nε-Dansyl-L-lysine

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About This Item

Empirical Formula (Hill Notation):
C18H25N3O4S
CAS Number:
Molecular Weight:
379.47
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

application(s)

detection

storage temp.

−20°C

SMILES string

[H][C@](N)(CCCCNS(=O)(=O)c1cccc2c(cccc12)N(C)C)C(O)=O

InChI

1S/C18H25N3O4S/c1-21(2)16-10-5-8-14-13(16)7-6-11-17(14)26(24,25)20-12-4-3-9-15(19)18(22)23/h5-8,10-11,15,20H,3-4,9,12,19H2,1-2H3,(H,22,23)/t15-/m0/s1

InChI key

VQPRNSWQIAHPMS-HNNXBMFYSA-N

Biochem/physiol Actions

Nepsilon-Dansyl-L-lysine is used to study binding conformations of drugs to human serum albumin. Nepsilon-Dansyl-L-lysine is used as the template molecule to form molecularly imprinted monolayers (MIMs) useful to produce optical biosensor recognition elements

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Xiao Li et al.
Langmuir : the ACS journal of surfaces and colloids, 22(23), 9658-9663 (2006-11-01)
This article describes a new two-step methodology for preparing thiol monolayers having artificial recognition sites for dansylated amino acids on gold optical biosensor surfaces. Nepsilon-Dansyl-L-lysine (DK) was used as the template molecule to form molecularly imprinted monolayers (MIMs). Impact factors
G M Humphries et al.
The Journal of membrane biology, 77(2), 115-122 (1984-01-01)
The ability to resist staining by N epsilon-dansyl-L-lysine is tenuously maintained in the majority of live nucleated cells taken from tissues concerned with immune function. Resistance is lost under a variety of nonphysiological conditions known to, or likely to, cause
H Kim et al.
FEBS letters, 346(2-3), 246-250 (1994-06-13)
For the purpose of engineering the antibody combining site, mapping residues that are involved in antigen binding provide us with valuable information. By use of 13C NMR spectroscopy with selectively 13C-labeled Fv fragments, we have established a general strategy to
T Hayamizu et al.
Journal of chromatography. B, Biomedical sciences and applications, 710(1-2), 211-218 (1998-08-01)
Dansyl amino acids having a free amino group and an asymmetric carbon atom were examined as a labeling reagent for chiral compounds containing carboxylic moieties to realize enantiomeric separation as well as fluorimetric determination. We tested dansyllysine by reacting it
G C Rice et al.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 1(2), 185-191 (1985-04-01)
We have employed the nontoxic fluorescent membrane probe, N-sigma-dansyl-L-lysine (DL) to study the effect of mild (45.5 degrees C) heat shock on a variety of mammalian cell lines. It has been previously proposed by Humphries and Lovejoy (1983) that DL

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