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CLS431485

Corning® Spin-X® UF concentrators

Spin-X UF 6 for samples up to 6mL; 50K MWCO

Synonym(s):

centrifuge columns, desalting columns

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About This Item

UNSPSC Code:
41104916
NACRES:
NB.13

material

polycarbonate housing
polyethersulfone membrane

description

white, polypropylene screw cap

sterility

non-sterile

packaging

case of 25 ea

manufacturer/tradename

Corning 431485

H × diam.

122 mm × 17 mm

membrane surface area

2.5 cm2

tube size

15 mL , conical bottom

working volume

6 mL

pore size

50 kDa MWCO

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General description

Corning Spin-X UF Concentrators:
  • Corning® Spin-X® UF centrifugal concentrators offer a simple, one step procedure for concentrating or desalting proteins and other biomolecules with 90% or better recovery
  • The vertical membrane design and thin channel filtration chamber minimizes membrane fouling and provides fast, high speed concentrating, even with particle laden solutions
  • Integrated dead stop design eliminates the risk of spinning to dryness; no respinning necessary
  • Choice of three sizes for greater flexibility: Spin-X UF 500 for samples up to 500 μL, Spin-X UF 6 for samples up to 6mL, Spin-X UF 20 for samples up to 20 mL (14 mL if using fixed angle rotors)
  • Low binding polyethersulfone (PES) membranes are available with five molecular weight cut-offs (MWCO): 5K, 10K, 30K, 50K and 100K to meet all your concentrating needs. Note: Choose a MWCO one-half to one-third smaller than the protein to be concentrated
  • The MWCO and graduations are printed right on the side of the concentrator tube to avoid confusion

Summary:
  • Spin-X UF 500 for samples up to 500 μL
  • Spin-X UF 6 for samples up to 6 mL
  • Spin-X UF 20 for samples up to 20 mL (14 mL if using fixed angle rotors)

Note: Spin-X UF 500 concentrators require fixed angle rotors. Minimum rotor angle is 40º

Application

Key Spin-X UF Concentrator Applications:
  • Concentration, desalting of proteins, enzymes, monoclonal antibodies, immunoglobulins
  • Removal of labeled amino acids and nucleotides
  • Deproteinization of samples
  • HPLC sample preparation
  • Recovery of biomolecules from cell culture supernatants, lysates
  • Concentrating virus from cell culture medium

Legal Information

Corning is a registered trademark of Corning, Inc.
SPIN-X is a registered trademark of Corning, Inc.

Certificates of Analysis (COA)

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Hongshan Zhang et al.
Nucleic acids research, 48(14), 7834-7843 (2020-07-06)
RADX is a mammalian single-stranded DNA-binding protein that stabilizes telomeres and stalled replication forks. Cellular biology studies have shown that the balance between RADX and Replication Protein A (RPA) is critical for DNA replication integrity. RADX is also a negative

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