C8480
D-erythro-Ceramine C8
98% (TLC), solid
Synonym(s):
N-Octyl-D-sphingosine
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25 MG
HUF 262,500.00
HUF 262,500.00
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25 MG
HUF 262,500.00
About This Item
Empirical Formula (Hill Notation):
C26H53NO2
Molecular Weight:
411.70
MDL number:
UNSPSC Code:
12352104
PubChem Substance ID:
NACRES:
NA.77
HUF 262,500.00
Please contact Customer Service for Availability
Quality Level
Assay
98% (TLC)
form
solid
color
white
solubility
DMSO: 25 mg/mL
ethanol: 25 mg/mL
storage temp.
−20°C
SMILES string
CCCCCCCCCCCCC\C=C\[C@@H](O)[C@H](CO)NCCCCCCCC
InChI
1S/C26H53NO2/c1-3-5-7-9-11-12-13-14-15-16-17-18-20-22-26(29)25(24-28)27-23-21-19-10-8-6-4-2/h20,22,25-29H,3-19,21,23-24H2,1-2H3/b22-20+/t25-,26+/m0/s1
InChI key
CSRGRGSMEUKQSD-XQAXIDAFSA-N
Biochem/physiol Actions
Inert to ceramidases; induces peak DNA fragmentation in 6 hrs; induces apoptosis in U937 cells.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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N Karasavvas et al.
European journal of biochemistry, 236(2), 729-737 (1996-03-01)
We investigated the ability of N-octanoyl-sphingosine (C8-Cer) stereoisomers, N-octanoyl-DL-erythro-dihydrosphingosine (DL-e-DHC8-Cer), and a new ceramide derivative, N-octyl-D-erythro-sphingosine (D-e-C8-Ceramine), to induce apoptosis in U937 cells. We found the C8-Cer stereoisomers to be stereospecific with the D- and L-threo stereoisomers being severalfold more
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