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C8355

Sigma-Aldrich

D-erythro-Ceramide C8 1-phosphate

≥93% (HPLC), powder or solid

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About This Item

Empirical Formula (Hill Notation):
C26H52NO6P
Molecular Weight:
505.67
MDL number:
MFCD00270917
UNSPSC Code:
12352211
PubChem Substance ID:
329775167
NACRES:
NA.77

Quality Level

200

Assay

≥93% (HPLC)

form

film
powder or solid

color

white to off-white

solubility

DMSO: 15 mg/mL
ethanol: 20 mg/mL, clear to hazy (Colorless to faint yellow)

storage temp.

−20°C

SMILES string

CCCCCCCCCCCCC\C=C\[C@@H](O)[C@H](COP(O)(O)=O)NC(=O)CCCCCCC

InChI

1S/C26H52NO6P/c1-3-5-7-9-10-11-12-13-14-15-16-18-19-21-25(28)24(23-33-34(30,31)32)27-26(29)22-20-17-8-6-4-2/h19,21,24-25,28H,3-18,20,22-23H2,1-2H3,(H,27,29)(H2,30,31,32)/b21-19+/t24-,25+/m0/s1

InChI key

VSSNYUXSRXINIP-WRBRXSDHSA-N

Biochem/physiol Actions

Cell permeable stimulator of DNA synthesis in cultured fibroblasts; antagonizes mitogenic activity.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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A Gomez-Muñoz et al.
Molecular pharmacology, 47(5), 833-839 (1995-05-01)
Ceramide and ceramide-1-phosphate are sphingolipid analogues of diacylglycerol and phosphatidate, respectively, and they are putative second messengers of agonist-stimulated sphingomyelin metabolism. The interactions of exogenous cell-permeable ceramides and ceramide-1-phosphates in modifying DNA synthesis and signal transduction were investigated in Rat-1

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