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C7252

Sigma-Aldrich

D-(+)-Cellobiose

≥98% (HPLC)

Synonym(s):

β-D-Glc-(1→4)-D-Glc, 4-O-β-D-Glucopyranosyl-D-glucose

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About This Item

Empirical Formula (Hill Notation):
C12H22O11
CAS Number:
Molecular Weight:
342.30
Beilstein:
93795
EC Number:
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.21

biological source

plant

Assay

≥98% (HPLC)

form

powder

optical activity

[α]/D 34±1, c = 10% (w/v) in water

technique(s)

HPLC: suitable

color

beige

mp

239 °C (dec.) (lit.)

solubility

water: 50 mg/mL, clear, colorless

storage temp.

room temp

SMILES string

OC[C@@H](O)[C@@H](O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)C=O

InChI

1S/C12H22O11/c13-1-4(16)7(18)11(5(17)2-14)23-12-10(21)9(20)8(19)6(3-15)22-12/h1,4-12,14-21H,2-3H2/t4-,5+,6+,7+,8+,9-,10+,11+,12-/m0/s1

InChI key

DKXNBNKWCZZMJT-WELRSGGNSA-N

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General description

Cellobiose, a disaccharide, is made up of two d-glucose molecules linked by a β-1,4-glycosidic bond. This reducing sugar can mutarotate and is produced by hydrolysis of cellulose.

Application

D-(+)-Cellobiose has been used:
  • as a component in test sugar solution for cellobiose-mannitol permeability test
  • in the preparation of lyophilization solutions to study its ability to protect lyophilized β-galactosidase from enzymatic activity loss and secondary structure changes during storage
  • as a fermentation/growth substrate to grow Clostridium thermocellum to study its impacts on the qualitative and quantitative changes in cellulosome composition

Other Notes

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Shuen Hon et al.
Metabolic engineering communications, 3, 120-129 (2016-04-22)
Clostridium thermocellum is a promising candidate for ethanol production from cellulosic biomass, but requires metabolic engineering to improve ethanol yield. A key gene in the ethanol production pathway is the bifunctional aldehyde and alcohol dehydrogenase, adhE. To explore the effects
Mireia Lopez-Siles et al.
Applied and environmental microbiology, 78(2), 420-428 (2011-11-22)
Faecalibacterium prausnitzii is one of the most abundant commensal bacteria in the healthy human large intestine, but information on genetic diversity and substrate utilization is limited. Here, we examine the phylogeny, phenotypic characteristics, and influence of gut environmental factors on
Stuart M Linton et al.
Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 184(4), 449-468 (2014-02-26)
The digestive ability of four sympatric land crabs species (the gecarcinids, Gecarcoidea natalis and Discoplax celeste and the anomurans, Birgus latro and Coenobita perlatus) was examined by determining the activity of their digestive enzymes. The gecarcinids are detritivores that consume
Babu Raman et al.
PloS one, 4(4), e5271-e5271 (2009-04-23)
Economic feasibility and sustainability of lignocellulosic ethanol production requires the development of robust microorganisms that can efficiently degrade and convert plant biomass to ethanol. The anaerobic thermophilic bacterium Clostridium thermocellum is a candidate microorganism as it is capable of hydrolyzing
Benjamin J Allardyce et al.
The Journal of experimental biology, 213(Pt 17), 2950-2957 (2010-08-17)
A 160 kDa enzyme with beta-glucosidase activity was purified from the midgut gland of the land crab Gecarcoidea natalis. The enzyme was capable of releasing glucose progressively from cellobiose, cellotriose or cellotetraose. Although beta-glucosidases (EC 3.2.1.21) have some activity towards

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