A6470

N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide

≥97% (HPLC), powder

• Synonym(s): Ac-IEPD-pNA
• Empirical Formula (Hill Notation): C₂₈H₃₈N₆O₁₁
• CAS Number: 216757-29-8
• Molecular Weight: 634.63
• MDL number: MFCD02259221
• UNSPSC Code: 12352209
• PubChem Substance ID: 329770895
• NACRES: NA.77

Properties

• Quality Level: 200
• Assay: ≥97% (HPLC)
• form: powder
• solubility: DMSO: soluble
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)Nc2ccc(cc2)[N+]([O-])=O
• InChI: 1S/C28H38N6O11/c1-4-15(2)24(29-16(3)35)27(42)31-19(11-12-22(36)37)28(43)33-13-5-6-21(33)26(41)32-20(14-23(38)39)25(40)30-17-7-9-18(10-8-17)34(44)45/h7-10,15,19-21,24H,4-6,11-14H2,1-3H3,(H,29,35)(H,30,40)(H,31,42)(H,32,41)(H,36,37)(H,38,39)/t15-,19-,20-,21-,24-/m0/s1
• InChI key: YXEIIOVAGGAMCZ-NYMCBPKFSA-N
• Gene Information: human ... CARD8(22900) , CASP8(841) , CASP8AP2(9994) , CFLAR(8837) , GZMB(3002) ; mouse ... CFLAR(117279) , GZMB(171528) ; rat ... CASP8(12370) , CFLAR(12633) , GZMB(14939) , RGD1561819(502004) , RGD1562700(502007)

Description

Amino Acid Sequence

NAc-Ile-Glu-Pro-Asp-pNA

Substrates

Chromogenic substrate for caspase 8 and granzyme B.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves