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83875

Sigma-Aldrich

D-Ribose 5-phosphate disodium salt dihydrate

≥99% (TLC)

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About This Item

Empirical Formula (Hill Notation):
C5H9Na2O8P · 2H2O
CAS Number:
Molecular Weight:
310.10
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.25

Assay

≥99% (TLC)

form

powder

impurities

≤5% solvent (ethanol, methanol)
6-15% water

color

light yellow

solubility

H2O: 50 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

O.O.[Na+].[Na+].O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@@H](O)C=O

InChI

1S/C5H11O8P.2Na.2H2O/c6-1-3(7)5(9)4(8)2-13-14(10,11)12;;;;/h1,3-5,7-9H,2H2,(H2,10,11,12);;;2*1H2/q;2*+1;;/p-2/t3-,4+,5-;;;;/m0..../s1

InChI key

ROFJYRUKQPRHKK-WFAHMUOKSA-L

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Application

D-Ribose 5-phosphate is used as a substrate to identify, differentiate and characterize ribose-5-phosphate isomerase(s) and phosphopentomutase(s). Ribose 5-phosphate is used to study the processes and effects of glycation in vivo and in vitro.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
For the synthesis of 5-phospho-D-ribosyl α-1-pyrophosphate; Isolation of transketolase

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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A. Gross et al.
Journal of the American Chemical Society, 105, 7428-7428 (1983)
A Mocali et al.
European journal of biochemistry, 180(1), 213-219 (1989-03-01)
Transketolase has been purified for the first time from human leukocytes, according to a new procedure which consists of three conventional steps. The enzyme was finally detached from CM-cellulose by specific elution with a D-xylulose-5-phosphate/D-ribose-5-phosphate mixture and the isolated product
Nisreen Wahwah et al.
Scientific reports, 10(1), 19907-19907 (2020-11-18)
Cisplatin is a mainstay of cancer chemotherapy. It forms DNA adducts, thereby activating poly(ADP-ribose) polymerases (PARPs) to initiate DNA repair. The PARP substrate NAD+ is synthesized from 5-phosphoribose-1-pyrophosphate (PRPP), and we found that treating cells for 6 h with cisplatin reduced

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