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IRMM315

4-Deoxynivalenol in acetonitrile

IRMM®, certified reference material

Synonym(s):

Deoxynivalenol solution, 3α,7α,15-Trihydroxy-12,13-epoxytrichothec-9-en-8-one, DON, Vomitoxin

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About This Item

Empirical Formula (Hill Notation):
C15H20O6
CAS Number:
51481-10-8
Molecular Weight:
296.32
EC Number:
200-835-2
MDL number:
MFCD09039270
UNSPSC Code:
41116107
PubChem Substance ID:
329815693
NACRES:
NA.24

grade

certified reference material

Agency

IRMM®

manufacturer/tradename

JRC

application(s)

general analytical

format

matrix material

storage temp.

2-8°C

SMILES string

CC1=C[C@H]2O[C@@H]3[C@H](O)C[C@@](C)([C@]34CO4)[C@@]2(CO)[C@H](O)C1=O

InChI

1S/C15H20O6/c1-7-3-9-14(5-16,11(19)10(7)18)13(2)4-8(17)12(21-9)15(13)6-20-15/h3,8-9,11-12,16-17,19H,4-6H2,1-2H3/t8-,9-,11-,12-,13-,14-,15+/m1/s1

InChI key

LINOMUASTDIRTM-QGRHZQQGSA-N

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General description

Check out our entire range of trichothecene type mycotoxin reference materials

Analysis Note

For more information please see:
IRMM315

Legal Information

IRMM is a registered trademark of European Commission

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

35.6 °F - closed cup

Flash Point(C)

2.0 °C - closed cup

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Patricia M Cano et al.
PloS one, 8(1), e53647-e53647 (2013-01-18)
Deoxynivalenol (DON) is a mycotoxin produced by Fusarium species which is commonly found in temperate regions worldwide as a natural contaminant of cereals. It is of great concern not only in terms of economic losses but also in terms of
Dirk Rohweder et al.
Archives of animal nutrition, 67(1), 37-47 (2013-01-23)
Fusarium infections do not only affect the grain, but also the rest of the plant, which result in contamination of plants with the mycotoxin deoxynivalenol (DON). The bioavailability of DON may be influenced by the matrix due to the differences
Joelma Lucioli et al.
Toxicon : official journal of the International Society on Toxinology, 66, 31-36 (2013-02-14)
Trichothecenes induce changes in the intestinal barrier function through decreased expression of cell junction proteins and apoptosis of enterocytes. The mitogen activated protein kinases (MAPK) play an important role in the signaling pathways of cell turnover and differentiation. Using ex
Amal Halawa et al.
Archives of animal nutrition, 67(2), 134-146 (2013-03-26)
Deoxynivalenol (DON) is one of the most important trichothecenes, due to its worldwide distribution and common contamination of animal feed. It mainly affects the gastrointestinal tract and the immune system with a high susceptibility for swine. Lipopolysaccharides (LPS) are endotoxins
Brenna M Flannery et al.
Toxicology, 304, 192-198 (2013-01-10)
Consumption of the trichothecene deoxynivalenol (DON) suppresses growth in experimental animals - an adverse effect that was used to establish the tolerable daily intake for this toxin. DON ingestion has been recently found to suppress plasma insulin-like growth factor acid-labile
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