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74412

Supelco

Trolamine salicylate

analytical standard

Synonym(s):

TEA salicylate, Triethanolamine salicylate, Triethanolaminium salicylate, Tris(2-hydroxyethyl)ammonium 2-hydroxybenzoate

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About This Item

Empirical Formula (Hill Notation):
C13H21NO6
CAS Number:
2174-16-5
Molecular Weight:
287.31
Beilstein:
7451205
EC Number:
218-531-3
UNSPSC Code:
41116107
NACRES:
NA.24

grade

analytical standard

Quality Level

100

Assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

SMILES string

OCC[NH+](CCO)CCO.Oc1ccccc1C([O-])=O

InChI

1S/C7H6O3.C6H15NO3/c8-6-4-2-1-3-5(6)7(9)10;8-4-1-7(2-5-9)3-6-10/h1-4,8H,(H,9,10);8-10H,1-6H2

InChI key

UEVAMYPIMMOEFW-UHFFFAOYSA-N

General description

Trolamine salicylate is a type of salicylate derivative, which is a sunscreen agent and a topical analgesic.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H315,H319,H335

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG5443
BCCC0314
BCBV6072

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P Morra et al.
The Annals of pharmacotherapy, 30(9), 935-940 (1996-09-01)
To compare the rate and extent of systemic salicylate absorption following single and multiple applications of two topically applied analgesics, one containing methyl salicylate and the other containing trolamine salicylate. Two-period, two-treatment, randomized, crossover, multiple-dose study in healthy men and
J L Rabinowitz et al.
Journal of clinical pharmacology, 22(1), 42-48 (1982-01-01)
The local, articular, and systemic absorption of oral and topical salicylates was studied in dogs and humans using radioisotope techniques. Topical triethanolamine 14C-salicylate was found capable of percutaneous absorption into the knee joint and surrounding tissues. In dogs, topical salicylate
G J Algozzine et al.
JAMA, 247(9), 1311-1313 (1982-03-05)
Twenty-five patients with symptomatic osteoarthritis (OA) of the knee were treated topically for one week with either 10% trolamine salicylate cream or placebo cream in a randomized double-blind crossover study. No significant difference was found in subjective or objective measures
J R Baldwin et al.
Journal of pharmaceutical sciences, 73(7), 1002-1004 (1984-07-01)
Studies to determine the extent of local tissue penetration of topically applied trolamine [14C]salicylate were conducted in domestic pigs. The preparation was applied onto a 100-cm2 shaved area of skin overlying the biceps femoris at a concentration of 0.7 mg
Trolamine salicylate cream in osteoarthritis.
JAMA, 248(13), 1577-1578 (1982-10-01)
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