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Key Documents

07-167

Sigma-Aldrich

Anti-Blys/TALL-1/BAFF/THANK Antibody

Upstate®, from rabbit

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

purified antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

Specificity

Blys/TALL-1/BAFF/THANK

Immunogen

peptide corresponding to amino acids 254-269 of human Blys (EEGDELQLAIPRENAQ)

Application

Anti-Blys/TALL-1/BAFF/THANK Antibody is an antibody against Blys/TALL-1/BAFF/THANK for use in WB.

Quality

routinely evaluated by immunoblot on RIPA lysates from Jurkat cells or HeLa nuclear extract

Target description

32kDa

Physical form

Format: Purified
PBS containing 0.05% BSA and 0.05% sodium azide.

Analysis Note

Control
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

10 - Combustible liquids


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Proinflammatory mediators elicit secretion of the intracellular B-lymphocyte stimulator pool (BLyS) that is stored in activated neutrophils: implications for inflammatory diseases.
Scapini, P; Carletto, A; Nardelli, B; Calzetti, F; Roschke, V; Merigo, F; Tamassia et al.
Blood null
Epithelial cells trigger frontline immunoglobulin class switching through a pathway regulated by the inhibitor SLPI.
Weifeng Xu, Bing He, April Chiu, Amy Chadburn, Meimei Shan, Malwina Buldys, Aihao Ding et al.
Nature Immunology null
Patrizia Scapini et al.
The Journal of experimental medicine, 197(3), 297-302 (2003-02-05)
B lymphocyte stimulator (BLyS) is a novel member of the TNF ligand superfamily that is important in B cell maturation and survival. We demonstrate that human neutrophils, after incubation with G-CSF or, less efficiently, IFN gamma, express high levels of
Macrophage- and dendritic cell--dependent regulation of human B-cell proliferation requires the TNF family ligand BAFF.
Craxton, A; Magaletti, D; Ryan, EJ; Clark, EA
Blood null
F Mackay et al.
The Journal of experimental medicine, 190(11), 1697-1710 (1999-12-10)
The cause of many autoimmune and inflammatory diseases is unresolved, although dysregulated production of tumor necrosis factor (TNF) family members appears to be important in many cases. BAFF, a new member of the TNF family, binds to B cells and

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