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850541P

Avanti

MEGA-9

Avanti Research™ - A Croda Brand 850541P, powder

Synonym(s):

N-nonanoyl-N-methylglucamine

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About This Item

CAS Number:
85261-19-4
UNSPSC Code:
12161902
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 g (850541P-1g)

manufacturer/tradename

Avanti Research™ - A Croda Brand 850541P

application(s)

microbiology

shipped in

dry ice

storage temp.

−20°C

SMILES string

OCC(O)C(O)C(O)C(O)CN(C)C(CCCCCCCC)=O

InChI

1S/C16H33NO6/c1-3-4-5-6-7-8-9-14(21)17(2)10-12(19)15(22)16(23)13(20)11-18/h12-13,15-16,18-20,22-23H,3-11H2,1-2H3/t12-,13+,15+,16+/m0/s1

InChI key

GCRLIVCNZWDCDE-SJXGUFTOSA-N

General description

Acyl-N-methylglucamide (MEGA) detergents are non-ionic detergents that provide a good starting point for your structural biology work. The hydrophilic head groups offer ample strength to extract proteins while still providing the capability to stabilize proteins in solution and promote crystal growth.
MEGA-9 (N-nonanoyl-N-methyl-D-glucamine) is a nonionic sugar-based surfactant. It is a membrane solubilizer and can forms vesicles.

Application

MEGA-9 may be used as a component of PBS.

Packaging

20 mL Clear Glass Screw Cap Vial (850541P-1g)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Hb (64-76) epitope binds in different registers and lengths to I-Ek and I-Ak
Vidal K, et al.
Molecular Immunology, 37(5), 203-212 (2000)
Self-aggregation of MEGA-9 (N-nonanoyl-N-methyl-d-glucamine) in aqueous medium: physicochemistry of interfacial and solution behaviors with special reference to formation energetics and micelle microenvironment
Pan A, et al.
The Journal of Physical Chemistry B, 117(25), 7578-7592 (2013)
J M Hierrezuelo et al.
Langmuir : the ACS journal of surfaces and colloids, 20(24), 10419-10426 (2004-11-17)
The mixed micellization between the nonionic surfactant decanoyl-N-methylglucamide (MEGA-10) and the common sodium dodecyl sulfate (SDS) in aqueous solutions of 0.1 M NaCl was investigated by the fluorescence probe method. The critical micelle concentrations were determined by the pyrene 1:3
J E Hildreth
The Biochemical journal, 207(2), 363-366 (1982-11-01)
N-d-Gluco-N-methylalkanamide detergents have been synthesized. The detergents, which were produced in high yield and at low cost, compared favourably in biochemical studies with commonly used non-ionic detergents, including a chemically related n-alkyl glucoside. The ease of removal by dialysis, high
Matthew A Churchward et al.
Proteome science, 3(1), 5-5 (2005-06-09)
The analysis of hydrophobic membrane proteins by two-dimensional gel electrophoresis has long been hampered by the concept of inherent difficulty due to solubility issues. We have optimized extraction protocols by varying the detergent composition of the solubilization buffer with a
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