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Key Documents

N27306

Sigma-Aldrich

2-Nitrotoluene

≥99%

Synonym(s):

1-Methyl-2-nitrobenzene

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About This Item

Linear Formula:
CH3C6H4NO2
CAS Number:
Molecular Weight:
137.14
Beilstein:
1907580
MDL number:
UNSPSC Code:
12352102
PubChem Substance ID:

Assay

≥99%

refractive index

n20/D 1.546 (lit.)

bp

225 °C (lit.)

mp

−4-−3 °C (lit.)

density

1.163 g/mL at 25 °C (lit.)

SMILES string

Cc1ccccc1[N+]([O-])=O

InChI

1S/C7H7NO2/c1-6-4-2-3-5-7(6)8(9)10/h2-5H,1H3

InChI key

PLAZTCDQAHEYBI-UHFFFAOYSA-N

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H L Hong et al.
Toxicology and applied pharmacology, 191(3), 227-234 (2003-09-19)
The most prominent neoplastic lesions in mice in the 2-year studies of o-nitrotoluene and riddelliine were hemangiosarcomas. Fifteen o-nitrotoluene-induced hemangiosarcomas of the skeletal muscle, subcutaneous tissue, and mesentery; 12 riddelliine-induced hemangiosarcomas of the liver; and 15 spontaneous subcutaneous hemangiosarcomas were
Akané E Hartenbach et al.
Environmental science & technology, 42(22), 8352-8359 (2008-12-17)
Compound-specific nitrogen isotope analysis was shown to be a promising tool for the quantitative assessment of abiotic reduction of nitroaromatic contaminants (NACs) under anoxic conditions. To assess the magnitude and variability of 15N fractionation for reactions with dissolved reductants, we
Christopher R Jones et al.
Carcinogenesis, 24(4), 779-787 (2003-05-03)
2-Nitrotoluene (2NT) is an important commercial chemical intermediate. A recent National Toxicology Programme (NTP)-study demonstrated clear evidence of carcinogenic activity of 2NT in rats. In the present study male WELS-Fohm rats were dosed chronically with 2NT, 5 days a week
Christine A Rabinovitch-Deere et al.
Applied and environmental microbiology, 78(7), 2306-2315 (2012-01-31)
Acidovorax sp. strain JS42 is able to utilize 2-nitrotoluene (2NT) as its sole carbon, nitrogen, and energy source. We report here that strain JS42 is chemotactic to 2NT and that the response is increased when cells are grown on compounds
R C Sills et al.
Carcinogenesis, 25(4), 605-612 (2003-12-23)
In the previous 500 2-year chemical bioassays within the National Toxicology Program, large intestinal tumors (cecal carcinomas) related to chemical exposure have not been observed in B6C3F1 mice. The recently completed o-nitrotoluene study provided the first cecal tumor response and

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