900572
Biotinylated isoxazole
95%
Synonym(s):
6-(5-(Thiophen-2-yl)isoxazole-3-carboxamido)hexyl 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoate, B-Isox, B-isox
Sign Into View Organizational & Contract Pricing
All Photos(2)
About This Item
Empirical Formula (Hill Notation):
C24H32N4O5S2
CAS Number:
Molecular Weight:
520.66
MDL number:
UNSPSC Code:
12352108
NACRES:
NA.22
Recommended Products
Application
When exposed to cells or tissue lysates, biotinylated isoxazole (b-isox) was shown to precipitate RNA-binding proteins with significant overlap to the components of RNA granules. By reversibly aggregating and disaggregating structures similar to RNA granules, b-isox has lent insight to polypeptides necessary for the reversible aggregation of RNA-binding proteins.
This product was previously listed as T511617.
This product was previously listed as T511617.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Phosphorylation-regulated binding of RNA polymerase II to fibrous polymers of low-complexity domains.
Kwon I, et al.
Cell, 155(5), 1049-1060 (2013)
Cell-free formation of RNA granules: bound RNAs identify features and components of cellular assemblies.
Han T W, et al.
Cell, 149(4), 768-779 (2012)
Poly-dipeptides encoded by the C9orf72 repeats bind nucleoli, impede RNA biogenesis, and kill cells.
Ilmin Kwon et al.
Science (New York, N.Y.), 345(6201), 1139-1145 (2014-08-02)
Many RNA regulatory proteins controlling pre-messenger RNA splicing contain serine:arginine (SR) repeats. Here, we found that these SR domains bound hydrogel droplets composed of fibrous polymers of the low-complexity domain of heterogeneous ribonucleoprotein A2 (hnRNPA2). Hydrogel binding was reversed upon
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service